Chemotherapy Certification
Doxorubicin - ANSCardiotoxic
TISSUE VESICANT
Baseline MUGA and general dose (CONCERN at 550 mg/m2)
URINE=RED
IF EXTRAVASATION OCCURS= cool/ice + Totect
Idamycin - ANSCardiotoxic (cardiomyopathy)
Bleomycin - ANSAVOID oxygen supplementation
Methotrexate - ANS*Leukovorin decreases cytotoxicity*
Pemetrexed - ANSVitamin B12 & folic acid supplements to decrease toxicity
Fludarabine - ANSImmunosuppression
Thioguanine - ANSBone Marrow Suppression
Stomatitis/Mucositis
5-FU - ANS*Stomatitis
Bone marrow melancholy
*Diarrhea
Mucositis
Capeticibine - ANS***Pro-drug that converts 5FU in liver
Stomatitis & mucositis
Palmar-plantar erythrodysthesias (hand foot syndrome)
Cytarabine or Cytosine Arabinoside - ANSCerebellar neurotoxicity
Gemcitabine - ANSRadiosensitizer DO NOT GIVE W/ RADIATION, except at very low doses
Carmustine - ANS***Solvent is alcohol
Alcohol sensivity is an issue
Mix ONLY in 0.9% NaCl
Carboplatin - ANSDose with the aid of CALVERT components
Allergic response multiplied from 1-27% in pts receiving >6-7 guides
Doxorubicin - ANSCardiotoxic
TISSUE VESICANT
Baseline MUGA and general dose (CONCERN at 550 mg/m2)
URINE=RED
IF EXTRAVASATION OCCURS= cool/ice + Totect
Idamycin - ANSCardiotoxic (cardiomyopathy)
Bleomycin - ANSAVOID oxygen supplementation
Methotrexate - ANS*Leukovorin decreases cytotoxicity*
Pemetrexed - ANSVitamin B12 & folic acid supplements to decrease toxicity
Fludarabine - ANSImmunosuppression
Thioguanine - ANSBone Marrow Suppression
Stomatitis/Mucositis
5-FU - ANS*Stomatitis
Bone marrow melancholy
*Diarrhea
Mucositis
Capeticibine - ANS***Pro-drug that converts 5FU in liver
Stomatitis & mucositis
Palmar-plantar erythrodysthesias (hand foot syndrome)
Cytarabine or Cytosine Arabinoside - ANSCerebellar neurotoxicity
Gemcitabine - ANSRadiosensitizer DO NOT GIVE W/ RADIATION, except at very low doses
Carmustine - ANS***Solvent is alcohol
Alcohol sensivity is an issue
Mix ONLY in 0.9% NaCl
Carboplatin - ANSDose with the aid of CALVERT components
Allergic response multiplied from 1-27% in pts receiving >6-7 guides