EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024
NU 607 Module 2 Study Guide with
Complete Solutions
Pharmacodynamics - Answer✔✔-the study of the biochemical and physiologic effects of drugs
and the molecular mechanisms by which those effects are produced; study of what drugs do to
the body and how they do it
Mechanisms of action - Answer✔✔-ways by which drugs can produce therapeutic effects; once
the drug is at the site of action, it can increase or decrease the rate at which cells or tissues
function
Dose-response relationship - Answer✔✔-the relationship between the size of an administered
dose and the intensity of the response produced
Efficacy - Answer✔✔-the largest effect that a drug can produce
True/False: A drug with a very high maximal efficacy does not mean it is always more desirable
than one with a lower efficacy - Answer✔✔-True
Potency - Answer✔✔-the amount of drug we must give to elicit an effect
True/False: A drug that is more potent will produce a therapeutic effect at a lower dose
compared to a drug with the higher dose - Answer✔✔-True
Page 1/9
, EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024
Drugs act through receptors by binding to them. By binding to the receptor, the drug can do
what 2 things? - Answer✔✔-1. initiate (produce) a response
2. block (prevent) a response
Affinity - Answer✔✔-the degree to which a drug molecule binds to a receptor and elicits a
response; the strength of the attraction between a drug & its receptor
Drug binding sites are primarily on __________, ___________, and _______________ -
Answer✔✔-transmembrane proteins, glycoproteins, enzymes
4 primary receptor families - Answer✔✔-Cell membrane-embedded enzymes
Ligand-gated ion channels
G protein-coupled receptor systems
Transcription factors (nuclear receptors)
Cell membrane-embedded enzymes - Answer✔✔-Receptors that span the cell membrane;
domain is located on the cell surface with the enzyme's catalytic site inside; response occurs in
seconds. i.e. insulin
Ligand-gated ion channel - Answer✔✔-receptors that span the cell membrane, function to
regulate flow of ions into and out of cells. each channel is specific for a particular ion. domain is
located on the cell surface. responses to activation are extremely fast, usually occurring in
milliseconds
Page 2/9
NU 607 Module 2 Study Guide with
Complete Solutions
Pharmacodynamics - Answer✔✔-the study of the biochemical and physiologic effects of drugs
and the molecular mechanisms by which those effects are produced; study of what drugs do to
the body and how they do it
Mechanisms of action - Answer✔✔-ways by which drugs can produce therapeutic effects; once
the drug is at the site of action, it can increase or decrease the rate at which cells or tissues
function
Dose-response relationship - Answer✔✔-the relationship between the size of an administered
dose and the intensity of the response produced
Efficacy - Answer✔✔-the largest effect that a drug can produce
True/False: A drug with a very high maximal efficacy does not mean it is always more desirable
than one with a lower efficacy - Answer✔✔-True
Potency - Answer✔✔-the amount of drug we must give to elicit an effect
True/False: A drug that is more potent will produce a therapeutic effect at a lower dose
compared to a drug with the higher dose - Answer✔✔-True
Page 1/9
, EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024
Drugs act through receptors by binding to them. By binding to the receptor, the drug can do
what 2 things? - Answer✔✔-1. initiate (produce) a response
2. block (prevent) a response
Affinity - Answer✔✔-the degree to which a drug molecule binds to a receptor and elicits a
response; the strength of the attraction between a drug & its receptor
Drug binding sites are primarily on __________, ___________, and _______________ -
Answer✔✔-transmembrane proteins, glycoproteins, enzymes
4 primary receptor families - Answer✔✔-Cell membrane-embedded enzymes
Ligand-gated ion channels
G protein-coupled receptor systems
Transcription factors (nuclear receptors)
Cell membrane-embedded enzymes - Answer✔✔-Receptors that span the cell membrane;
domain is located on the cell surface with the enzyme's catalytic site inside; response occurs in
seconds. i.e. insulin
Ligand-gated ion channel - Answer✔✔-receptors that span the cell membrane, function to
regulate flow of ions into and out of cells. each channel is specific for a particular ion. domain is
located on the cell surface. responses to activation are extremely fast, usually occurring in
milliseconds
Page 2/9
