What amino acids are converted to a-ketoglutarate? Correct Ans-- glutamate
- glutamine
- arginine
- histidine
- proline
Enzyme for arginine > ornithine Correct Ans-Arginase
What are the byproducts of asparagine > aspartate? Correct Ans-- H2O
- NH4
What are the byproducts of aspartate > oxaloacetate? Correct Ans-- a-ketoglutarate
- glutamate
What are the byproducts of arginine > ornithine? Correct Ans-- H2O
- urea
What amino acids are converted to succinyl CoA? Correct Ans-- methionine
- isoleucine
- threonine
- valine
, BMSC 230: Final Exam with Verified Answers
What are the intermediates of methionine, valine, & isoleucine to succinyl CoA? Correct
Ans-- propionyl CoA
- methylmalonyl CoA
What are the steps of degradation of methionine? Correct Ans-- methionine
- S-adenosylmethionine (SAM)
- S-adenosylhomocysteine
- homocysteine
- cystathionine
- a-ketobutyrate
- propionyl CoA
- succinyl CoA
Enzyme for methionine > S-adenosylmethionine Correct Ans-Methionine adenosyl
transferase
What enzyme allows serine to be directly deaminated to pyruvate + NH4? Correct Ans-
Serine dehydratase
What enzyme allows threonine to be directle deaminated to a-ketobutyrate + NH4?
Correct Ans-Threonine dehydratase
, BMSC 230: Final Exam with Verified Answers
Where are branched-chain amino acids mostly degraded? Correct Ans-- muscle
- adipose tissue
- kidney
- brain
What are branched-chain amino acids converted to first? By what? Correct Ans-- ketoacids
- branched-chain aminotransferase
What complex catalyzes oxidate decarboxylation of branched-chain amino acids? What does
this release? Correct Ans-- branched-chain a-keto acid dehydrogenase complex
- releases the carboxyl group as CO2 & producing acyl-CoA deriviatives
What are the acyl CoA derivatives of leucine? Correct Ans-- a-ketoisocaproate
- acetyl CoA + acetoacetate
What are the acyl CoA derivatives of isoleucine? Correct Ans-- 2-keto-3-methylvalerate
- acetyl CoA + propionyl CoA
What are the acyl CoA derivatives of valine? Correct Ans-- a-ketoisovalerate
- propionyl CoA