Blood banking - Minor blood groups Review Questions with complete Solutions Graded A+
010 - Answers ISBT number of Diego blood system
Dia antigen - Answers Antigen which acts as a useful tool in anthropologic studies of Mongolian ancestry
Anion exchange molecule (AE-1) - Answers Dia and Dib antigens are located where?
Hereditary spherocytosis, congenital acanthocytosis, Southeast Asian ovalocytosis - Answers Defects of
AE-1 and shows weak expression of Diego antigen
Dia+ - Answers Diego antigen which is prevalent in American Indians, Japanese, and Chinese
Dib+ - Answers Diego antigen which is prevalent in Whites
011 - Answers ISBT number of Cartwright blood group system
Yta - Answers High-incidence Cartwright antigen which is present in 99.8% of the general population
Ytb - Answers Low-incidence Cartwright antigen which is present in 8% of the general population
Erythrocyte acetylcholinesterase - Answers Where are Cartwright antigens found on?
Yes, significant (reactive in IAT) - Answers Are Cartwright antibodies clinically significant?
012 - Answers ISBT number of Xg blood group system
Xga - Answers Only antigen identified with no antithetical partner
Short arm of X chromosome - Answers Genes that code for Xg allele is located on?
CD99 molecule - Answers Xg antigen is carried by a protein with cell adhesion properties that has been
demonstrated to have homology with?
Xga - Answers Approximately 89% of the female population expresses this antigen while only 66% of the
male population expresses it
013 - Answers ISBT number of the Scianna blood group system
Sc2 - Answers The prevalence of this Scianna antigen in Northern Europeans is 1% but is higher in the
Mennonite population.
Anti-Sc3 - Answers What is the clinically significant antibody in the Scianna blood group system?
Sc-1,-2,-3 - Answers This rare null phenotype has been observed in the Marshall Islands and New Guinea
014 - Answers ISBT number of the Dombrock blood group system
Mono-ADP-Ribosyltransferase 4 - Answers Where are Dombrock antigens carried on?
, Yes, caused moderate transfusion reactions - Answers Are Dombrock antibodies clinically significant?
015 - Answers ISBT number of Colton blood group system
Aquaporin 1 (AQP1), Channel-forming integral protein (CHIP) - Answers Where are Colton antigens
carried on?
Anti-Coa and anti-Cob - Answers Colton antibodies which are IgG and cause acute to delayed transfusion
reactions
Anti-CO3 - Answers Colton antibody which is IgG and associated with severe HDFN
016 - Answers ISBT number of Landsteiner-Wiener blood group system
Intracellular adhesion molecule 4 (ICAM4) - Answers Where are LW antigens carried on?
LW(a-b-) - Answers LW has a phenotypic relationship with the D antigen; Rhnull RBCs type as ______
Rhnull - Answers Anti-LW differs from anti-D because it agglutinates Rh(+) and Rh(-) except ______
DTT treated - Answers Anti-LW differs from anti-D because it does not react with _____ RBCs
017 - Answers ISBT number of Chido-Rodgers blood system
C4A, C4B - Answers Rodgers and Chido antigens are respectively found on the C4D fragments of the
____ and ____ glycoproteins of the C4 complement component
Anti-Ch/Rg - Answers These antibodies were formerly grouped as HTLA and usually stimulated in multi-
transfused individuals lacking one or more of the corresponding antigens
020 - Answers ISBT number of the Gerbich blood system
Gerbich phenotype (Ge:-2,-3,4) - Answers What phenotype of the Gerbich system is common in Papua
New Guineans, Europeans, Africans, Native Americans, Japanese, and Polynesians?
Yus phenotype (Ge:-2,3,4) - Answers What phenotype of the Gerbich system is common in Mexicans and
Israelis?
Leach phenotype (Ge:-2,-3,-4) - Answers What phenotype of the Gerbich system is common in Gerbich
null within Papua New Guinea
Elliptocytosis - Answers What type of poikilocytosis is found in Gerbich null phenotype?
Glycophorins C and/or D - Answers Where are GE antigens expressed on?
021 - Answers ISBT number of the Cromer blood group system?
Decay accelerating factor (DAF) or CD55 - Answers Where are Cromer antigens located on?
010 - Answers ISBT number of Diego blood system
Dia antigen - Answers Antigen which acts as a useful tool in anthropologic studies of Mongolian ancestry
Anion exchange molecule (AE-1) - Answers Dia and Dib antigens are located where?
Hereditary spherocytosis, congenital acanthocytosis, Southeast Asian ovalocytosis - Answers Defects of
AE-1 and shows weak expression of Diego antigen
Dia+ - Answers Diego antigen which is prevalent in American Indians, Japanese, and Chinese
Dib+ - Answers Diego antigen which is prevalent in Whites
011 - Answers ISBT number of Cartwright blood group system
Yta - Answers High-incidence Cartwright antigen which is present in 99.8% of the general population
Ytb - Answers Low-incidence Cartwright antigen which is present in 8% of the general population
Erythrocyte acetylcholinesterase - Answers Where are Cartwright antigens found on?
Yes, significant (reactive in IAT) - Answers Are Cartwright antibodies clinically significant?
012 - Answers ISBT number of Xg blood group system
Xga - Answers Only antigen identified with no antithetical partner
Short arm of X chromosome - Answers Genes that code for Xg allele is located on?
CD99 molecule - Answers Xg antigen is carried by a protein with cell adhesion properties that has been
demonstrated to have homology with?
Xga - Answers Approximately 89% of the female population expresses this antigen while only 66% of the
male population expresses it
013 - Answers ISBT number of the Scianna blood group system
Sc2 - Answers The prevalence of this Scianna antigen in Northern Europeans is 1% but is higher in the
Mennonite population.
Anti-Sc3 - Answers What is the clinically significant antibody in the Scianna blood group system?
Sc-1,-2,-3 - Answers This rare null phenotype has been observed in the Marshall Islands and New Guinea
014 - Answers ISBT number of the Dombrock blood group system
Mono-ADP-Ribosyltransferase 4 - Answers Where are Dombrock antigens carried on?
, Yes, caused moderate transfusion reactions - Answers Are Dombrock antibodies clinically significant?
015 - Answers ISBT number of Colton blood group system
Aquaporin 1 (AQP1), Channel-forming integral protein (CHIP) - Answers Where are Colton antigens
carried on?
Anti-Coa and anti-Cob - Answers Colton antibodies which are IgG and cause acute to delayed transfusion
reactions
Anti-CO3 - Answers Colton antibody which is IgG and associated with severe HDFN
016 - Answers ISBT number of Landsteiner-Wiener blood group system
Intracellular adhesion molecule 4 (ICAM4) - Answers Where are LW antigens carried on?
LW(a-b-) - Answers LW has a phenotypic relationship with the D antigen; Rhnull RBCs type as ______
Rhnull - Answers Anti-LW differs from anti-D because it agglutinates Rh(+) and Rh(-) except ______
DTT treated - Answers Anti-LW differs from anti-D because it does not react with _____ RBCs
017 - Answers ISBT number of Chido-Rodgers blood system
C4A, C4B - Answers Rodgers and Chido antigens are respectively found on the C4D fragments of the
____ and ____ glycoproteins of the C4 complement component
Anti-Ch/Rg - Answers These antibodies were formerly grouped as HTLA and usually stimulated in multi-
transfused individuals lacking one or more of the corresponding antigens
020 - Answers ISBT number of the Gerbich blood system
Gerbich phenotype (Ge:-2,-3,4) - Answers What phenotype of the Gerbich system is common in Papua
New Guineans, Europeans, Africans, Native Americans, Japanese, and Polynesians?
Yus phenotype (Ge:-2,3,4) - Answers What phenotype of the Gerbich system is common in Mexicans and
Israelis?
Leach phenotype (Ge:-2,-3,-4) - Answers What phenotype of the Gerbich system is common in Gerbich
null within Papua New Guinea
Elliptocytosis - Answers What type of poikilocytosis is found in Gerbich null phenotype?
Glycophorins C and/or D - Answers Where are GE antigens expressed on?
021 - Answers ISBT number of the Cromer blood group system?
Decay accelerating factor (DAF) or CD55 - Answers Where are Cromer antigens located on?
