NURSING PHARMACOLOGY
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, a. Absorption - ANSWERS-the process by which drug molecules move from
their site of administration to the blood
b. Affinity - ANSWERS-the ability of some tissues to attract, accumulate and
store drugs in high concentrations relative to other tissues
c. Blood-brain barrier - ANSWERS-Blood vessels (capillaries) that selectively
let certain substances enter the brain tissue and keep other substances out
d. Diffusion - ANSWERS-process by which molecules tend to move from an
area where they are more concentrated to an area where they are less
concentrated
e. Distribution - ANSWERS-the transport of drugs throughout the body after
they are absorbed
f. Drug-protein complexes - ANSWERS-formed when a drugh that binds
reversibly to a plasma protein, particularly albumin, that makes the drug
unavailable for distribution to its site of action
g. Enterohepatic recirculation - ANSWERS-recycling of drugs and other
substances by the circulation of bile through the intestine and liver
h. Enzyme induction - ANSWERS-process by whick a drug increases the activity
of the hepatic microsomal enzymes
i. Excretion - ANSWERS-the process of removing substances from the body
j. First-pass effect - ANSWERS-mechanism whereby drugs are absorbed enter
into the hepatic portal circulation and are inactivated by the liver before
they reach the general circulation
MODULE 1
0
, a. Absorption - ANSWERS-the process by which drug molecules move from
their site of administration to the blood
b. Affinity - ANSWERS-the ability of some tissues to attract, accumulate and
store drugs in high concentrations relative to other tissues
c. Blood-brain barrier - ANSWERS-Blood vessels (capillaries) that selectively
let certain substances enter the brain tissue and keep other substances out
d. Diffusion - ANSWERS-process by which molecules tend to move from an
area where they are more concentrated to an area where they are less
concentrated
e. Distribution - ANSWERS-the transport of drugs throughout the body after
they are absorbed
f. Drug-protein complexes - ANSWERS-formed when a drugh that binds
reversibly to a plasma protein, particularly albumin, that makes the drug
unavailable for distribution to its site of action
g. Enterohepatic recirculation - ANSWERS-recycling of drugs and other
substances by the circulation of bile through the intestine and liver
h. Enzyme induction - ANSWERS-process by whick a drug increases the activity
of the hepatic microsomal enzymes
i. Excretion - ANSWERS-the process of removing substances from the body
j. First-pass effect - ANSWERS-mechanism whereby drugs are absorbed enter
into the hepatic portal circulation and are inactivated by the liver before
they reach the general circulation
