Jessica Willard
STUDENT NAME _____________________________________
Nitroglycerin
MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________
antianginal agent
CATEGORY CLASS ______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action Therapeutic Use
in chronic stable exertional angina, nitroglycerin dilates veins and treatment of acute angina attack
decrease venous return(preload) which decreases cardiac oxygen.
-In Prinzmetals or vasospastic angina, nitroglycerin prevents or -prophylaxis of chronic stable angina or
reduces coronary atery spasm, thus increasing oxygen supply.
Oxygen is not decreased.
variant angina.
Complications Medication Administration
headache -provide continuous cardiac and
-orthostatic hypotension bloop pressure monitoring.
-reflex tachycardia - use lowest dose needed to
-tolerance achieve effect.
-monitor vital signs
Contraindications/Precautions
-pregnancy risk category B for tablets and category C for capsules,IV, spray,ointment,patch.
-contraindicated for clients who have hypersensitivity to nitrates.
-contraindicated in clients who have severe anemia, closed angle glaucoma and traumatic head injury,
med can increase intracranial pressure.
-use cautiously in clients taking antihypertensive meds and have hyperthyroidism or kidney or liver
dysfunction.
Nursing Interventions
-inhibitors of phoshodiesterase type 5 for ED administered w/nitroglycerin can intensify the nitroglycerin
induces vasodilators and result in life threatening hypotension provide continuous cardiac and
bloop pressure monitoring.
- use lowest dose needed to
achieve effect.
-monitor vital signs
Interactions
-use of alcohol can contribute to the hypotensive effect
-antihypertensive meds (beta blockers, calcium channel
blockers, diuretics) can contribute to hypotensive effect.
Client Education
do not crush or chew oral nitrogylcerin
tablets
or sublingual is ineffective if swallowed
Evaluation of Medication Effectiveness -stop taking long acting nitroglycerin
abruptly.
-prevention and termination of acute anginal attacks. -place patch on hairless area of skin and
- long-term management of stable angina rotate sites.
-control of perioperative blood pressure. -remove patch at night to reduce risk of
-control of heart failure following acute MI. developing tolerance. Be medication free
10-12hr/day.
ACTIVE LEARNING TEMPLATES