BCH 361 Ch. 6 Study Questions with
100% Correct Verified Solutions|
Latest Update
Is chymotrypsin specific of nonspecific? - Answer specific
Describe how chymotrypsin works - Answer splits the peptide bonds only on
the carboxyl side of large hydrophobic residues (W,Y,F,M)
Is Thrombin specific or nonspecific? - Answer very specific
Describe how thrombin works - Answer catalyzes the hydrolysis of arginine-
glycine bonds in particular peptide sequence only
Where is thrombin found? - Answer in blood clotting
Name the 6 major types of enzymes - Answer oxidoreductases, transferases,
hydrolases, lyases, isomerases, ligases
Oxidoreductases - Answer catalyze oxidation-reduction rxns
examples of oxidoreductases - Answer dehydrogenase, transfer of elections, hydride
example of transferases - Answer kinases
,transferases - Answer move functional groups btw molecules
hydrolases - Answer cleave bonds w/ the addition of water
examples of hydrolases - Answer nucleases, peptidases, proteases, lipases, amylase
lyases - Answer remove atoms to form double bonds or add atoms to double bonds
examples of lyases - Answer enolase, fumarase
isomerases - Answer rearrange atoms w/in a molecule
examples of isomerases - Answer triose phosphate isomerase (reorganization
of carbons), mutase (move functional group intramolecularly)
ligases - Answer join 2 molecules at the expense of ATP
examples of ligases - Answer DNA ligase, DNA polymerases, DNA polyerases
How are most enzymes named? - Answer after their substrates and the rxns they
catalyze (both forward and backward); w/ suffix "-ase"
cofactors - Answer small molecules or ions that some enzymes require for activity
apoenzyme - Answer w/out the cofactor, inactive enzyme
, holoenzyme - Answer complete, catalytically active enzyme w/ its cofactor
coenzymes - Answer small organic molecules derived from vitamins
co-substrate - Answer loosely bound (diffuse in and out)
prosthetic groups - Answer A tightly or covalently bound coenzyme
Name the enzyme for Zn^2 - Answer carbonic anhydrase
Name the enzyme for biotin - Answer pyruvate carboxylase
Name the enzyme for coenzyme A - Answer acetyl CoA carboxylase
Name the enzyme for nicotinamide adenine dinucleotide (NAD+) - Answer lactate
dehydrogenase
Name the enzyme for Flavin adenine nucleotide (FAD) - Answer monoamine oxidase
Name the thiamine pyrophosphate (TPP) - Answer pyruvate dehydrogenase
How do enzymes speed up the rate of rxns? - Answer by reducing the transition
state energy but enzymes do not alter the free energy change (Delta G) of rxn
What does the free energy change (Delta G) at a given condition depend on? -
Answer nature of rxn and the reactants and products' concentrations
100% Correct Verified Solutions|
Latest Update
Is chymotrypsin specific of nonspecific? - Answer specific
Describe how chymotrypsin works - Answer splits the peptide bonds only on
the carboxyl side of large hydrophobic residues (W,Y,F,M)
Is Thrombin specific or nonspecific? - Answer very specific
Describe how thrombin works - Answer catalyzes the hydrolysis of arginine-
glycine bonds in particular peptide sequence only
Where is thrombin found? - Answer in blood clotting
Name the 6 major types of enzymes - Answer oxidoreductases, transferases,
hydrolases, lyases, isomerases, ligases
Oxidoreductases - Answer catalyze oxidation-reduction rxns
examples of oxidoreductases - Answer dehydrogenase, transfer of elections, hydride
example of transferases - Answer kinases
,transferases - Answer move functional groups btw molecules
hydrolases - Answer cleave bonds w/ the addition of water
examples of hydrolases - Answer nucleases, peptidases, proteases, lipases, amylase
lyases - Answer remove atoms to form double bonds or add atoms to double bonds
examples of lyases - Answer enolase, fumarase
isomerases - Answer rearrange atoms w/in a molecule
examples of isomerases - Answer triose phosphate isomerase (reorganization
of carbons), mutase (move functional group intramolecularly)
ligases - Answer join 2 molecules at the expense of ATP
examples of ligases - Answer DNA ligase, DNA polymerases, DNA polyerases
How are most enzymes named? - Answer after their substrates and the rxns they
catalyze (both forward and backward); w/ suffix "-ase"
cofactors - Answer small molecules or ions that some enzymes require for activity
apoenzyme - Answer w/out the cofactor, inactive enzyme
, holoenzyme - Answer complete, catalytically active enzyme w/ its cofactor
coenzymes - Answer small organic molecules derived from vitamins
co-substrate - Answer loosely bound (diffuse in and out)
prosthetic groups - Answer A tightly or covalently bound coenzyme
Name the enzyme for Zn^2 - Answer carbonic anhydrase
Name the enzyme for biotin - Answer pyruvate carboxylase
Name the enzyme for coenzyme A - Answer acetyl CoA carboxylase
Name the enzyme for nicotinamide adenine dinucleotide (NAD+) - Answer lactate
dehydrogenase
Name the enzyme for Flavin adenine nucleotide (FAD) - Answer monoamine oxidase
Name the thiamine pyrophosphate (TPP) - Answer pyruvate dehydrogenase
How do enzymes speed up the rate of rxns? - Answer by reducing the transition
state energy but enzymes do not alter the free energy change (Delta G) of rxn
What does the free energy change (Delta G) at a given condition depend on? -
Answer nature of rxn and the reactants and products' concentrations
