TEST BANK For Edmunds' Pharmacology for the Primary Care
Provider, 5th Edition by Constance Visovsky
drug - ANSWER:chemical used to diagnose, treat, or prevent disease.
pharmacology - ANSWER:the study of drugs and their interactions with the body.
Sources - ANSWER:plants, animals, minerals, synthetic
Drug Names - ANSWER:Chemical, Generic, Brand
assay - ANSWER:test that determines the amount and purity of a given chemical in a
preparation in
the laboratory.
bioassay - ANSWER:test to ascertain a drug's availability in a biological model.
dose packaging - ANSWER:medication packages that contain a single dose for a
single patient.
teratogenic drug - ANSWER:medication that may deform or kill the fetus.
free drug availability - ANSWER:proportion of a drug available in the body to cause
either desired or undesired effects.
pharmacokinetics - ANSWER:how drugs are transported into and out of the body
pharmacodynamics - ANSWER:how a drug interacts with the body to cause its
effects.
6 rights of medication administration - ANSWER:1. Medication
2.Dose
3. Time
4. Route
5. Patient
6. Documentation
Pharmokinetic Process - ANSWER:1. Absorption
2. Distribution
3. Biotransformation
4. Elimination
Special Considerations - ANSWER:1. Pregnant Patients
2. Pediatric Patients
, 3. Geriatric Patients
carrier-mediated diffusion - ANSWER:process in which carrier proteins transport
large molecules across the cell membrane; also called facilitated diffusion.
passive transport - ANSWER:movement of a substance without the use of energy.
diffusion - ANSWER:the movement of molecules through a membrane from an area
of greater
concentration to an area of lesser concentration.
osmosis - ANSWER:the passage of a solvent, such as water, through a membrane;
the diffusion
pattern of water in which molecules move to equalite concentrations on both sides
of a
membrane; movement of solvent in a solution from an area of lower solute
concentration to an area of higher solute concentration.
filtration - ANSWER:movement of water out of the plasma across the capillary
membrane into the
interstitial space; movement of molecules across a membrane from an area of higher
pressure to an area of lower pressure.
ionize - ANSWER:to become electrically charged or polar.
bioavailability - ANSWER:amount of a drug that is still active after it reaches its target
tissue.
blood-brain barrier - ANSWER:tight junctions of the capillary endothelial cells in the
central nervous system vasculature through which only non-protein-bound, highly
lipid-soluble drugs can pass.
placental barrier - ANSWER:biochemical barrier at the maternal/fetal interface that
restricts certain molecules.
metabolism - ANSWER:the total changes that take place during physiological
processes.
biotransformation - ANSWER:Name given to the metabolism of drugs
prodrug (parent drug) - ANSWER:medication that is not active when administered,
but whose biotransformation converts it into active metabolites.
first-pass effect - ANSWER:the liver's partial or complete inactivation of a drug
before it reaches the systemic circulation.
Provider, 5th Edition by Constance Visovsky
drug - ANSWER:chemical used to diagnose, treat, or prevent disease.
pharmacology - ANSWER:the study of drugs and their interactions with the body.
Sources - ANSWER:plants, animals, minerals, synthetic
Drug Names - ANSWER:Chemical, Generic, Brand
assay - ANSWER:test that determines the amount and purity of a given chemical in a
preparation in
the laboratory.
bioassay - ANSWER:test to ascertain a drug's availability in a biological model.
dose packaging - ANSWER:medication packages that contain a single dose for a
single patient.
teratogenic drug - ANSWER:medication that may deform or kill the fetus.
free drug availability - ANSWER:proportion of a drug available in the body to cause
either desired or undesired effects.
pharmacokinetics - ANSWER:how drugs are transported into and out of the body
pharmacodynamics - ANSWER:how a drug interacts with the body to cause its
effects.
6 rights of medication administration - ANSWER:1. Medication
2.Dose
3. Time
4. Route
5. Patient
6. Documentation
Pharmokinetic Process - ANSWER:1. Absorption
2. Distribution
3. Biotransformation
4. Elimination
Special Considerations - ANSWER:1. Pregnant Patients
2. Pediatric Patients
, 3. Geriatric Patients
carrier-mediated diffusion - ANSWER:process in which carrier proteins transport
large molecules across the cell membrane; also called facilitated diffusion.
passive transport - ANSWER:movement of a substance without the use of energy.
diffusion - ANSWER:the movement of molecules through a membrane from an area
of greater
concentration to an area of lesser concentration.
osmosis - ANSWER:the passage of a solvent, such as water, through a membrane;
the diffusion
pattern of water in which molecules move to equalite concentrations on both sides
of a
membrane; movement of solvent in a solution from an area of lower solute
concentration to an area of higher solute concentration.
filtration - ANSWER:movement of water out of the plasma across the capillary
membrane into the
interstitial space; movement of molecules across a membrane from an area of higher
pressure to an area of lower pressure.
ionize - ANSWER:to become electrically charged or polar.
bioavailability - ANSWER:amount of a drug that is still active after it reaches its target
tissue.
blood-brain barrier - ANSWER:tight junctions of the capillary endothelial cells in the
central nervous system vasculature through which only non-protein-bound, highly
lipid-soluble drugs can pass.
placental barrier - ANSWER:biochemical barrier at the maternal/fetal interface that
restricts certain molecules.
metabolism - ANSWER:the total changes that take place during physiological
processes.
biotransformation - ANSWER:Name given to the metabolism of drugs
prodrug (parent drug) - ANSWER:medication that is not active when administered,
but whose biotransformation converts it into active metabolites.
first-pass effect - ANSWER:the liver's partial or complete inactivation of a drug
before it reaches the systemic circulation.
