NUR 3145
Pharmacologic Basis of Nursing
LATEST MIDTERM REVIEW
© 2024/2025
,1. Which of the following receptors primarily mediates the effects
of opioid analgesics?
A) Alpha-1 adrenergic receptors
B) Mu receptors
C) Beta-2 adrenergic receptors
D) H1 histamine receptors
Answer: B) Mu receptors
Rationale: Mu receptors are primarily responsible for the
analgesic effects and are the main target for opioid medications.
2. What is the primary mechanism of action for ACE inhibitors?
A) Inhibition of calcium channel influx
B) Blockade of beta-adrenergic receptors
C) Inhibition of angiotensin-converting enzyme
D) Increased release of renin
Answer: C) Inhibition of angiotensin-converting enzyme
Rationale: ACE inhibitors block the conversion of angiotensin
I to angiotensin II, leading to vasodilation and reduced blood
pressure.
© 2024/2025
, 3. Which pharmacokinetic process describes the distribution of a
drug throughout the body's tissues?
A) Absorption
B) Distribution
C) Metabolism
D) Excretion
Answer: B) Distribution
Rationale: Distribution involves the delivery of the drug from
the bloodstream to various tissues and organs.
4. Which of the following medications is a beta-blocker used in
the management of hypertension?
A) Lisinopril
B) Metoprolol
C) Simvastatin
D) Furosemide
Answer: B) Metoprolol
Rationale: Metoprolol is a selective beta-1 adrenergic blocker
commonly prescribed for hypertension.
5. A nurse is administering an antiepileptic drug (AED). Which
of the following AEDs is associated with potentially serious skin
reactions, including Stevens-Johnson syndrome?
© 2024/2025
Pharmacologic Basis of Nursing
LATEST MIDTERM REVIEW
© 2024/2025
,1. Which of the following receptors primarily mediates the effects
of opioid analgesics?
A) Alpha-1 adrenergic receptors
B) Mu receptors
C) Beta-2 adrenergic receptors
D) H1 histamine receptors
Answer: B) Mu receptors
Rationale: Mu receptors are primarily responsible for the
analgesic effects and are the main target for opioid medications.
2. What is the primary mechanism of action for ACE inhibitors?
A) Inhibition of calcium channel influx
B) Blockade of beta-adrenergic receptors
C) Inhibition of angiotensin-converting enzyme
D) Increased release of renin
Answer: C) Inhibition of angiotensin-converting enzyme
Rationale: ACE inhibitors block the conversion of angiotensin
I to angiotensin II, leading to vasodilation and reduced blood
pressure.
© 2024/2025
, 3. Which pharmacokinetic process describes the distribution of a
drug throughout the body's tissues?
A) Absorption
B) Distribution
C) Metabolism
D) Excretion
Answer: B) Distribution
Rationale: Distribution involves the delivery of the drug from
the bloodstream to various tissues and organs.
4. Which of the following medications is a beta-blocker used in
the management of hypertension?
A) Lisinopril
B) Metoprolol
C) Simvastatin
D) Furosemide
Answer: B) Metoprolol
Rationale: Metoprolol is a selective beta-1 adrenergic blocker
commonly prescribed for hypertension.
5. A nurse is administering an antiepileptic drug (AED). Which
of the following AEDs is associated with potentially serious skin
reactions, including Stevens-Johnson syndrome?
© 2024/2025
