A cancer patient is seen in the emergency department
with high fevers and malaise for 2 days. She received
chemotherapy about 10 days ago. Her physical exam is
not revealing but her temperature is 103°F. A CBC shows
a hemoglobin of 10 g/dL, WBC 4000 with 10% polys, 5%
bands, 70% lymphs, 10% monos, and 5% other white or
unidentified cells. Platelets are 60,000/mm3. Which of
the following is NOT immediately appropriate?
a.blood cultures from different sites
b.electrolytes, liver and renal function tests
c.eask if she has been receiving granulocyte colony-
stimulating factor (G-CSF)
d.white blood cell transfusion ✔️✔️Answer: D
This patient has fever and neutropenia after
chemotherapy. Neutropenia is defined as an absolute
neutrophil count (ANC) under 1000/mm3, and a severe
neutropenia less than 500/mm3 is particularly
dangerous. These patients must be worked up quickly
and antibiotic and possibly additional therapy started as
soon as possible since the situation may be life-
threatening. While myelosuppressive drugs differ in the
,length of time between administration and the nadir of
the ANC, 10 to 14 days is typical. Multiple cultures from
different possible sites of origin for sepsis must be done
along with chest x-ray and other imaging as indicated by
examination. Broad-spectrum antibiotics, such as
ceftazidime or imipenem/cilastatin, should be started
after cultures are obtained. She should be asked if she
has been receiving G-CSF (Neupogen, Neulasta). WBC
transfusions are rarely used today since they have a very
short shelf life, do not last long in the circulation, and
may cause allergic reactions.
Which statement best describes acute respiratory
distress syndrome (ARDS)?
a.ARDS is caused by trauma only.
b.ARDS is sudden, progressive, and severe.
c.ARDS is caused by an illness only.
d.ARDS never results in lung scarring. ✔️✔️Answer: B
ARDS is sudden, progressive, and severe, and can even
lead to death.
, A forty-year-old female presents to the emergency
department (ED) complaining of chest pain. After triaging
the client, obtaining vital signs including a blood pressure
of 90/46, and establishing an adequate airway, what is
the next most important intervention for this client?
a. registering the patient into the system
b. ordering serum blood laboratory tests
c. placing the client on a cardiac monitor, administering
oxygen, and obtaining an electrocardiogram (EKG)
d. giving a sublingual nitroglycerin tablet for the
immediate relief of pain ✔️✔️C: A family member can
register the patient into the system, blood tests must be
done but can be done after the EKG, and, although
nitroglycerin is an appropriate intervention for pain, the
low blood pressure may need evaluation before choosing
to give nitroglycerin. The appropriate intervention is to
place the client on a cardiac monitor, give oxygen to
decrease cardiac workload, and obtain an EKG to
immediately evaluate the heart. The ED is a controlled
setting where a physician should be readily available to
look at the client, evaluate the cardiac monitor, and
interpret the EKG to determine further interventions.