2024/2025 EXAM QUESTIONS AND CORRECT ANSWERS
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Pure Food and Drug Act (1906) - answerForbade the manufacture, sale, and transportation of
adulterated or mislabeled foods and drugs.
Shirley Amendment of 1912 - answerPrevented fraudulent therapeutic claims by drug manufacturers
Harrison Act of 1914 - answerEstablished the word narcotic and required the use of a stamp on narcotic
drug containers. Also regulated the importation, manufacture, sale, and use of opium, codeine, and their
derivatives
Food, Drug, and Cosmetic Act of 1938 - answerA New drug could not be marketed until proven safe,
tested for toxicity, and required adverse drug effects to be reported.
Durham-Humphrey Amendment (1951) - answerReplaced Laws of 1938. Required designation of
whether or not the drug was prescription or OTC
Schedule I - answerThis type of drug has no accepted medical use in the United States and has a high
potential for abuse
,Schedule II drugs - answerAccepted for medical use but with severe restrictions (high potential for
abuse)
Schedule III drugs - answerHave low potential for abuse with an accepted medical use. Perscription only
Schedule IV - answerAbuse potential exists, but less than Sch III. Examples are: Ambien, Darvocet and
Lorazepam.
Schedule V drugs - answerLowest potential for abuse. May be sold OTC to people that show ID
Kefauver-Harris Amendment (1962) - answerRequires proof of safety and efficacy of a drug for approval
before marketing
Controlled Substances Act (1970) - answerReplaced all laws passed prior to it concerning drug control. 5
drug schedules put in place based on potential for abuse.
Poison Prevention Packaging Act (1970) - answerImplemented child resistant packaging
Drug Listing Act of 1972 - answerdrugs must have a National Drug Code number.
Drug Regulation and Reform Act of 1978 - answerQuicker development and distribution of new drugs
Orphan Drug Act of 1983 - answerEstablished funding for research of rare chronic illnesses for new and
old drugs.
Drug Price Competition and Patent Term Restoration Act of 1984 - answerEased requirements for
marketing generic drugs
Omnibus Budget Reconciliation Act (OBRA 1990) - answerMandated that OTC drugs be documented
Anabolic Steroid Control Act of 1990 - answerplaced all into category III drugs (CSA)
, Prescription Drug Amendments of 1992 - answerAllowed rapid approval of drugs for life-threatening
diseases
Food and Drug Administration Modernization Act of 1997 - answerAllowed rapid approval of drugs by
the FDA
Pharmacokinesis - answerthe movement of drugs through the body via absorbtion, distribution,
metabolism, and excretion
drug blood level - answeramount of a drug present in the blood
plasma binding - answerwhen proteins bind to drugs and decrease the amount of free-flowing drug in
the bloodstream allowing the drug to stay in the body for longer.
Examples of Sulfonamides - answerSulfamethoxazole, sulfisoxazole, sulfadiazine
Uses for Sulfonamides - answerTreating UTIs, Ulcerative colitis, 2nd and 3rd degree burns
Drugs that interact with Sulfonamides - answerOral anticoagulants, methotrexate, and hydantoins
What are the 4 groups of penicillin? - answerNatural penicillins, penicillinase-resistant penicillins,
aminopenicillins, extended-spectrum penicillins
Uses for Penicillins - answerUTIs, Septicemia, Meningitis, Intra-Abdominal infections, Sexually
Transmitted Infections (syphilis), Pneumonia and other respiratory infections
What variables can effect drug dosage? - answerWeight, Age, Height, Gender, Genetics, Diet
Another name for antianxiety drugs - answerAnxiolytics