BIOMG 3300 Unit 11 Objectives Questions with
Correct Answers
gluconeogenesis Correct Answer-a pathway used to create glucose from
non carobhydrate precursors
precursors for gluconeogensis Correct Answer-lactate, pyruvate,
glycerol, glucogenic amino acids
Which 3 glycolysis reactions are irreversible Correct Answer--
phosphorylation of glucose to glucose-6-phosphate
-phosphorylation of fructose-6-phosphate to fructose-1,6 bisphosphate
-phosphorylation of phosphoenol pyruvate to pyruvate
What is the cofactors used in the first bypass reaction for
gluconeogenesis? Correct Answer-biotin. Shifts CO2 and the energy
from the ATP in a bond. Hydrolyses it to provide energy for forward
reaction
In first bypass rxn for gluconeogenesis, why is the series of steps
important Correct Answer-the carboxylation and decarboxylation to
form PEP contributes to the overall irreversibility of the rxn
Is NADH usually found in the cytoplasm? Correct Answer-No, usually
found in the mitochondria
Needed in the cytoplasm for gluconeogenesis, so the first reaction must
put it there
, enzymes for first bypass rxn in gluconeogenesis Correct Answer--
pyruvate carboxylase, and PEP carboxykinase
enzyme for second bypass rxn in gluconeogensis Correct Answer--
fructose 1,6-biphosphotase-1 (hydrolysis of phosphate ester bond)
enzyme for third bypass rxn in gluconeogenesis Correct Answer--
glucose 6-phosphotase (hydrolysis of phosphate ester bond)
where do glycolysis and gluconeogenesis occur? Correct Answer-In the
cytoplasm
What is spent in gluconeogenesis? Correct Answer-2 ATP & 2GTP (first
bypass)
2ATP (3 phosphoglycerate to 1,3 bisphosphoglycerate)
2 NADH (1,3 bisphosphoglycerate to glyceraldehyde 3-phosphate)
futile cycle Correct Answer-a cycle which does no mechanical work,
energy released as heat
-occurs if glycolysis and gluconeogenesis occur @same time (prevented
w/ reciprocal regulation)
allosteric inhibitors for fructose 1,6 biphosphotase-1 Correct Answer-
AMP, ADP, fructose 2,6-biphosphate
Correct Answers
gluconeogenesis Correct Answer-a pathway used to create glucose from
non carobhydrate precursors
precursors for gluconeogensis Correct Answer-lactate, pyruvate,
glycerol, glucogenic amino acids
Which 3 glycolysis reactions are irreversible Correct Answer--
phosphorylation of glucose to glucose-6-phosphate
-phosphorylation of fructose-6-phosphate to fructose-1,6 bisphosphate
-phosphorylation of phosphoenol pyruvate to pyruvate
What is the cofactors used in the first bypass reaction for
gluconeogenesis? Correct Answer-biotin. Shifts CO2 and the energy
from the ATP in a bond. Hydrolyses it to provide energy for forward
reaction
In first bypass rxn for gluconeogenesis, why is the series of steps
important Correct Answer-the carboxylation and decarboxylation to
form PEP contributes to the overall irreversibility of the rxn
Is NADH usually found in the cytoplasm? Correct Answer-No, usually
found in the mitochondria
Needed in the cytoplasm for gluconeogenesis, so the first reaction must
put it there
, enzymes for first bypass rxn in gluconeogenesis Correct Answer--
pyruvate carboxylase, and PEP carboxykinase
enzyme for second bypass rxn in gluconeogensis Correct Answer--
fructose 1,6-biphosphotase-1 (hydrolysis of phosphate ester bond)
enzyme for third bypass rxn in gluconeogenesis Correct Answer--
glucose 6-phosphotase (hydrolysis of phosphate ester bond)
where do glycolysis and gluconeogenesis occur? Correct Answer-In the
cytoplasm
What is spent in gluconeogenesis? Correct Answer-2 ATP & 2GTP (first
bypass)
2ATP (3 phosphoglycerate to 1,3 bisphosphoglycerate)
2 NADH (1,3 bisphosphoglycerate to glyceraldehyde 3-phosphate)
futile cycle Correct Answer-a cycle which does no mechanical work,
energy released as heat
-occurs if glycolysis and gluconeogenesis occur @same time (prevented
w/ reciprocal regulation)
allosteric inhibitors for fructose 1,6 biphosphotase-1 Correct Answer-
AMP, ADP, fructose 2,6-biphosphate
