VTTP 434 FINAL QUESTIONS AND ANSWERS STUDY
GUIDE!!
thick filaments
Answers:myosin
thin filaments
Answers:actin, troponin, tropomyosin
Myofibril
Answers:the "straws" that make up a muscle cell
muscle fiber
Answers:a single muscle cell
M line
Answers:middle of sarcomere
A band
Answers:dark area-- thick filaments with some thin filament overlapping
I band
Answers:"illuminate band" light can pass through-- thin filaments and z disc only
Z disk
Answers:ends of the sarcomere where thin filaments attach
, H zone
Answers:only myosin
tropomyosin
Answers:"chaperone protein" that blocks actin binding sites to prevent
actin/myosin cross bridge cycling (skeletal muscle) also present in smooth muscle
but not as a chaperone proteing
troponin
Answers:3 binding sites- binds calcium, actin and tropomyosin. moves
tropomyosin out of the way when calcium binds to allow cross bridge cycling
sliding filament theory
Answers:z disc move inward toward m line with multiple cross bridge cycling.
ATP dependent
T tubule
Answers:extension of muscle cell plasma membrane that transmits APs through
muscle fiber
Dihydropyridine receptor
Answers:voltage sensitive receptor along t-tuble-- changes shape when AP is sent
down T tubule to activate ryanidine receptor
Ryanidine receptor
Answers:mechanically gated receptor on the lateral sac-- activated when DHPD
receptors change shape-- release Ca++ into cytosol
GUIDE!!
thick filaments
Answers:myosin
thin filaments
Answers:actin, troponin, tropomyosin
Myofibril
Answers:the "straws" that make up a muscle cell
muscle fiber
Answers:a single muscle cell
M line
Answers:middle of sarcomere
A band
Answers:dark area-- thick filaments with some thin filament overlapping
I band
Answers:"illuminate band" light can pass through-- thin filaments and z disc only
Z disk
Answers:ends of the sarcomere where thin filaments attach
, H zone
Answers:only myosin
tropomyosin
Answers:"chaperone protein" that blocks actin binding sites to prevent
actin/myosin cross bridge cycling (skeletal muscle) also present in smooth muscle
but not as a chaperone proteing
troponin
Answers:3 binding sites- binds calcium, actin and tropomyosin. moves
tropomyosin out of the way when calcium binds to allow cross bridge cycling
sliding filament theory
Answers:z disc move inward toward m line with multiple cross bridge cycling.
ATP dependent
T tubule
Answers:extension of muscle cell plasma membrane that transmits APs through
muscle fiber
Dihydropyridine receptor
Answers:voltage sensitive receptor along t-tuble-- changes shape when AP is sent
down T tubule to activate ryanidine receptor
Ryanidine receptor
Answers:mechanically gated receptor on the lateral sac-- activated when DHPD
receptors change shape-- release Ca++ into cytosol