Screening for Immunologic Disease
2 primary form of Lupus - ✅✅-Discoid and Systemic (SLE)
AIDS dementia complex
✅✅
(encephalopathy)
(affects CNS) - --Most common neuro complication and cause of mental
status changes
-similar to Alzheimer's but less effect memory loss and greater effect on TIME
RELATED SKILLS (ie play piano, reading); early symptoms include difficulty
concentration/memory, personality changes, irritability, apathy
Allergy -✅✅ -abnormal hypersensitivity that takes place when a foreign
substance is introduced into the body of a person
Anaphylaxis -✅✅-systemic manifestation of immediate hypersensitivity
Ankylosing Spondylitis (AS) - ✅✅--Chronic, progressive inflammatory d/o of
undetermined cause
-More an inflammation of fibrous tissue affecting the entheses, or insertions of
ligaments, tendons, and capsules into bone
• SI joints, spine, and large peripheral joints are primary affected
• Eye symptoms may precede spinal symptoms
CD4 markers - ✅✅ -receptors for the retrovirus, allows infection to enter the
cell
-HIV destroys these and takes over
-white blood cell
-also called helper T cells
Clinical s/s of Fibromyalgia Syndrome - ✅✅ -Widespread pain lasting >3
months and widespread local tenderness
-frequently: aches and pains, stiffness, swelling in soft tissue, tender points,
muscle spasms or nodules
-May be present: fatigue, AM stiffness, sleep disturbance
-Low threshold for pain, increased sensitivity to sensory stimuli
Complications w/ Ankylosing Spondylitis (AS) - ✅✅-•Stiff osteoporotic spine
prone to fracture from minor trauma
•Atlantoaxial subluxation
, •Progressive myelopathy develops from cord compression
•Spondylodiscitis: erosive and destructive lesions of vertebral bodies
•Cauda equina syndrome late, rare manifestation of disease
•Spinal stenosis occurs as result bony overgrowth of spinal ligaments/ facet
joints
Conjunctivitis -✅✅ -characterized by irritation with redness, tearing, and
burning usually lasting a few days; usually self-limiting
Contact dermatitis - ✅✅-No reaction with first exposure but antigens are
formed; subsequent exposure triggers hypersensitivity reactions
✅✅
Cytomegalovirus (CMV)
(affects PNS) - -herpes virus affects nerve roots, polyradiculopathy with
LE weakness progressing to flaccid paralysis
Deregulation of what is also a side effect of meds? - ✅✅-glucose
metabolism (insulin resistance, diabetes)
✅✅
Diffuse cutaneous
(Type of Scleroderma) - -more acute onset, with many constitutional
symptoms, arthritis, marked swelling of the hands and legs; widespread skin
thickening; internal organ problems common
Discoid lupus - ✅✅ -limited form of the disease confined to the skin
presenting as coin-shaped lesions, which are raised and scaly; rarely
develops into systemic form
Early signs of Spondyloarthropathy - ✅✅-Insidious onset LBP, 1st episode
often before age 30, each episode lasts months, pain increases after rest and
decreases with movement
Encephalopathy includes - ✅✅-AIDS dementia complex and motor
dysfunction (leads to falls)
Enthesitis -✅✅ -commonly occurs at insertions plantar aponeurosis and
Achilles tendon
Fibromyalgia syndrome - ✅✅ -Noninflammatory condition appearing with
generalized musculoskeletal pain in conjunction with tenderness to touch in a
2 primary form of Lupus - ✅✅-Discoid and Systemic (SLE)
AIDS dementia complex
✅✅
(encephalopathy)
(affects CNS) - --Most common neuro complication and cause of mental
status changes
-similar to Alzheimer's but less effect memory loss and greater effect on TIME
RELATED SKILLS (ie play piano, reading); early symptoms include difficulty
concentration/memory, personality changes, irritability, apathy
Allergy -✅✅ -abnormal hypersensitivity that takes place when a foreign
substance is introduced into the body of a person
Anaphylaxis -✅✅-systemic manifestation of immediate hypersensitivity
Ankylosing Spondylitis (AS) - ✅✅--Chronic, progressive inflammatory d/o of
undetermined cause
-More an inflammation of fibrous tissue affecting the entheses, or insertions of
ligaments, tendons, and capsules into bone
• SI joints, spine, and large peripheral joints are primary affected
• Eye symptoms may precede spinal symptoms
CD4 markers - ✅✅ -receptors for the retrovirus, allows infection to enter the
cell
-HIV destroys these and takes over
-white blood cell
-also called helper T cells
Clinical s/s of Fibromyalgia Syndrome - ✅✅ -Widespread pain lasting >3
months and widespread local tenderness
-frequently: aches and pains, stiffness, swelling in soft tissue, tender points,
muscle spasms or nodules
-May be present: fatigue, AM stiffness, sleep disturbance
-Low threshold for pain, increased sensitivity to sensory stimuli
Complications w/ Ankylosing Spondylitis (AS) - ✅✅-•Stiff osteoporotic spine
prone to fracture from minor trauma
•Atlantoaxial subluxation
, •Progressive myelopathy develops from cord compression
•Spondylodiscitis: erosive and destructive lesions of vertebral bodies
•Cauda equina syndrome late, rare manifestation of disease
•Spinal stenosis occurs as result bony overgrowth of spinal ligaments/ facet
joints
Conjunctivitis -✅✅ -characterized by irritation with redness, tearing, and
burning usually lasting a few days; usually self-limiting
Contact dermatitis - ✅✅-No reaction with first exposure but antigens are
formed; subsequent exposure triggers hypersensitivity reactions
✅✅
Cytomegalovirus (CMV)
(affects PNS) - -herpes virus affects nerve roots, polyradiculopathy with
LE weakness progressing to flaccid paralysis
Deregulation of what is also a side effect of meds? - ✅✅-glucose
metabolism (insulin resistance, diabetes)
✅✅
Diffuse cutaneous
(Type of Scleroderma) - -more acute onset, with many constitutional
symptoms, arthritis, marked swelling of the hands and legs; widespread skin
thickening; internal organ problems common
Discoid lupus - ✅✅ -limited form of the disease confined to the skin
presenting as coin-shaped lesions, which are raised and scaly; rarely
develops into systemic form
Early signs of Spondyloarthropathy - ✅✅-Insidious onset LBP, 1st episode
often before age 30, each episode lasts months, pain increases after rest and
decreases with movement
Encephalopathy includes - ✅✅-AIDS dementia complex and motor
dysfunction (leads to falls)
Enthesitis -✅✅ -commonly occurs at insertions plantar aponeurosis and
Achilles tendon
Fibromyalgia syndrome - ✅✅ -Noninflammatory condition appearing with
generalized musculoskeletal pain in conjunction with tenderness to touch in a
