LAT Final Exam Review Questions with well explained answers

3 R's - Answer-Replace Reduce Refine humane care - Answer-actions taken to assure that animals are treated according to high scientific and ethical standards animal care and use program - Answer-refers to policies, procedures, standards, organizational structure, staffing and practices implements What is the name of the program that helps to ensure that IACUC-approved procedures are being followed? - Answer-1. Postapproval monitoring program Which animals are NOT required by law to be accompanied by a health certificate when being shipped? - Answer-2. Laboratory mice Which costs are consistent throughout the budget period? - Answer-3. Fixed costs Which feature is required to be provided for dogs by the Animal Welfare Act (AWA)? - Answer-4. An exercise program If animals are to be euthanized at the end of a study, the method of euthanasia must be in accordance with the guidelines set up by the ____________. - Answer-5. American Veterinary Medical Association (AVMA) What is the definition of compliance? - Answer-6. Knowing the rules and following them What are the two federal agencies that require compliance with the Good Laboratory Practice (GLPs) Regulations? - Answer-7. Environmental Protection Agency & Food and Drug AdministrationAccording to the Good Laboratory Practices (GLPs) Regulations, what are the observations, measurements, and specimens related to a study called? - Answer-8. Raw data Which of the following describes what a facility must do to comply with the Animal Welfare Act (AWA)? - Answer-9. Animal Welfare Regulations What does the Institutional Animal Care and Use Committee (IACUC) have the authority to do? - Answer- 10. All of the above What is the name of the policy that an institution has in place to protect individuals who report animal welfare concerns? - Answer-11. Whistleblower policy Who can restrict or withdraw approval of the Animal Welfare Assurance if an institution fails at its responsibilities? - Answer-12. Office of Laboratory Animal Welfare (OLAW) What step must occur before a research study using animals begins? - Answer-13. An animal use protocol must be approved by the Institutional Animal Care and Use Committee (IACUC). What document is published by the Institute of Laboratory Animal Research and gives guidance on creating and implementing an institutional occupational health and safety program? - Answer-14. Occupational Health and Safety in the Care and Use of Research Animals Before a new drug is tested on human subjects, the drug is tested on animals in a phase that is called __________ testing. a. clinical - Answer-15. preclinical What record is needed to calculate per diems? - Answer-16. Animal census records What type of management program usually has the animal care program in a separate department that serves all the institution's animal care needs and requests? - Answer-17. Centralized management programWhat is the term that refers to the cost charged to maintain one unit, either one animal or one cage of animals, for one day? - Answer-18. Per diem rate