PHARMACOLOGY STUDY NOTES & EXAM
Ex: lactose intolerant, because they aren't making lactase to breakdown the lactose. So drinking lactose increases the production of lactase to break it down faster. Metabolizing it too fast= tolerant to that enzyme/drug. Inhibition: high plasma levels -drug inhibits the enzyme that breaks down so it increases the drug levels and increase side effects and plasma levels. Genetics: some people have slow breakdown or fast Disease: if liver is compromised, it may not breakdown drug effectively and drug levels will rise.;High Extraction Drugs - (first order metabolism: liver first!) Flow dependent: limiting factor is blood flow.;Low Extraction Drugs - Zero order drugs
Written for
- Institution
- Pharmacology
- Course
- Pharmacology
Document information
- Uploaded on
- May 21, 2024
- Number of pages
- 36
- Written in
- 2023/2024
- Type
- Exam (elaborations)
- Contains
- Questions & answers
Subjects
- renal function
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secretions lungs eye heart vasculature