NCLEX UWorld Pharmacology well answered graded A+

NCLEX UWorld Pharmacology Nephrotoxic Meds - correct answer -mycin antibiotics (aminoglycides) -keterolac (Toradol) -NSAIDs -digoxin Hepatotoxic Meds - correct answer -tylenol -NSAIDs Naloxone (Narcan) - correct answer -weans in 1-2 hours -IV or nasal spray -if unresponsive d/t anesthesia or opioids: administer oxygen, assess respiratory rate, notify HCP, prepare second dose Narcan, no need to call rapid response/code team NSAIDs - correct answer NON-STEROIDAL ANTI-INFLAMMATORY DRUGS -ex: aspirin, ibuprofen, naproxen -use at lowest dose necessary for short amount of time -risks: GI toxicity, kidney injury, HTN, heart failure, bleeding risk -do not use if hx cardiac problems Aspirin - correct answer -side effects: black tarry stools, ringing in ears (earliest sign), bruising, tachycardia, hypotension -ASA toxicity: treated with activated charcoal then IV sodium bicarbonate, sx disorientation/vomiting/diaphoresis/restlessness, tinnitus Opioids - correct answer -if taking extended release for chronic pain teach to take even if pain is not present -monitor respiratory status when taking with short acting opioids -IV 2-3 minute push then check 15-30 minutes after admin -nausea/vomiting usually subsides after initial treatment -take with food EX -morphine -hydrocodone -codeine -fentanyl -heroin (illegal substance) SE -sedation -respiratory depression -hypotension -constipation -risk for addiction Codeine - correct answer -narcotic used for acute pain or cough suppressant -can cause accumulation of secretions so do not prescribe to people with respiratory disorders Topical Medications - correct answer -allow 30 minutes before washing off to ensure medication is absorbed -avoid heat -local irritation is common Clozapine - correct answer -antipsychotic -increased risk for infection