CHEM 1005 Final Review Questions & Answers 100% Correct!

In the fasted state, fatty acyl-CoA are transported across the mitochondrial membrane. The transport of fatty acids via carnitine palmitoyl transferase I (CPTI) can be directly inhibited by which of the following compounds? a. Malonyl CoA b. Carnitine c. Acetyl CoA d. Palmitate - ANSWERSMalonyl CoA A 22-year-old woman engaging in a political protest goes on a hunger strike on a prominent corner in a city park. She refuses all offers of food except for water for the first 2 weeks. Under these conditions there is a decreased reliance on what pathway for fuel? - ANSWERSGluconeogenesis An 11-year-old girl is brought by the emergency department by her father. He reports she has recently been very thirsty and needing to make frequent trips to the bathroom. At her soccer game today, she complained of lightheadedness and the symptoms did not resolve after drinking a power beverage. A rapid dipstick test revealed glucose in her urine and further diagnostics were consistent with a diagnosis of Type 1 diabetes. Evaluation of the girl's liver would reveal an increased rate of which process? - ANSWERSKetogenesis Ketonuria, hyperglycemia, and severe acidosis are prime diagnostic indicators of the diagnosis of Type 1 diabetic ketoacidosis. Which compound are "ketone bodies" that would be elevated in serum and urine of a patient in this condition? - ANSWERSD-3 hydroxybutyrate and acetoacetate An individual is on hunger strike and has not eaten in 13 days. What best describes their metabolic state? - ANSWERSThe brain will be preferentially oxidizing ketones Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will activate what enzyme? - ANSWERSHormone sensitive lipase A 10-year-old boy is brought to the emergency department by his father. He reports his son has recently been very thirsty and needing to make frequent trips to the bathroom. Physical examination revealed a thin boy, in the 30th percentile for height and weight. A rapid dipstick test revealed glucose in his urine. Evaluation of this boy's blood would reveal decrease levels of which compound or hormone? - ANSWERSInsulin Which of the following is not a product of β-oxidation? - ANSWERSNADPH