NR 565 - CHAMBERLAIN - ADVANCED PHARMACOLOGY MIDTERM EXAM 2024 WITH 100% CORRECT ANSWERS

What is the cyp450 (cytochrome p450) --correct answer: liver enzyme system where medications are metabolized, can either be inducers or inhibitors, and create drug-drug interactions Cyp450 inducers --correct answer: speed up the metabolism of drugs (the drug is cleared faster), drug has a lesser effect (decrease blood levels of drug), elevates cyp450 enzymes Cyp450 inducers pneumonic --correct answer: "bullshit crap gps induces rage" Cyp450 inducer drug names --correct answer: barbituates, St John wort, carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas Cyp450 inhibitors --correct answer: inhibit metabolism, increase blood levels of medications Cyp450 pneumonic --correct answer: "Visa credit card debt inhibits spending on designers like ck to look gq" Cyp450 inhibitors drug names --correct answer: valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long-term consequences? --correct answer: 1st trimester (fetus most at risk d/t rapid growth) What is beer criteria? --correct answer: recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides