PRINCIPLES OF BACTERIAL VACCINES
Several bacterial diseases can be prevented by using immunizations that induce either active or
passive immunity.
This chapter focuses on a summary on vaccinations present and type of immunity provided.
ACTIVE IMMUNITY:
, Bacterial vaccines are composed of capsular polysaccharides, inactivated protein exotoxins
(toxoids), killed bacteria, or live, attenuated bacteria.
Capsular Polysaccharide Vaccines
1. Vaccine against Streptococcus pneumoniae
2. Capsular polysaccharide of 13 pneumococcal serotypes coupled to a carrier protein
(diphtheria toxoid)
3. Neisseria meningitidis
4. Haemophilus influenzae vaccine contains the type b polysaccharide conjugated to
diphtheria toxoid or other carrier protein.
5. Capsular polysaccharide of Salmonella typhi.