PC707 Final Safety Exam Questions With Correct Answers

First line for tx of constipation in pregnancy? - Answer bulk forming laxatives (citrucel) and glycerin suppositories. which constipation tx is contraindicated in pregnancy? - Answer Castor Oil is category X; rectal enemas are contraindicated Contraindications of Calciu carbonate antacids? - Answer contraindicated in presence of hypercalcemia and renal calculi adverse drug reactions for long-term use of PPIs? - Answer iron, b12, calcium deficiency - leads to osteoporosis, increased hip fractures. Also increased risk for c-diff, salmonella, and camphylobacter infections dose of an antacid should be separated from taking other medications by __ hours? - Answer 2 hours calcium and aluminum antacids can cause _____ - Answer constipation magnesium antacids can cause _____ - Answer diarrhea Schedule 2 controlled substance rx are written for a ___ day supply without refills - Answer 30 hydrocodone is a sched ____ drug - Answer 2 cox-2 inhibitors have a blackbox warning for what? - Answer increased risk for cardiovascular events milnacipran, duloxetine (cymbalta) and pregabalin (Lyrica) are the three drugs FDA approved for what? - Answer Fibromyalgia what are the 2 contraindications for metformin? - Answer renal disease or dysfunction and metabolic acidosis what is a major side effect of insulin? - Answer hypoglycemia 3 Rare but serious side effect of Bisphosphonates - Answer atypical fractures of the femur and hip, esophageal cancer, and osteonecrosis of the jaw - no dental implants OTIS - Organization of Teratology Information Specialists - good reference? - Answer yes physicians desk reference - good reference? - Answer no lactmed - good reference? - Answer yes Angioedema and anaphylaxis is what type of immune response? - Answer type 1 - IgE mediated, immediate type hypersensitivity The time period over which the drug concentration will decrease by half. - Answer half life