BIOL2400 Final Exam Practice Questions With Answers Latest 2023/2024
BIOL2400 Final Exam Practice Questions With Answers Latest 2023/2024. SNP data (the third codon position of a nuclear gene) from 1000 individuals on the enzyme Phosphoglucose isomerase (PGI) was collected from two populations of perch in two local rivers and also from Guelph Lake. As is usual for a SNP only two alleles were found: A1=C and A2=G. The genotype data for each population is given in the Table 1 below: Table 1: Perch genotypes: CC CG GG p(C) q(G) Eramosa R. .4 0.6 Speed R. .52 0.48 Guelph Lk .75 0.25 [a] Estimate the frequency of the A1 and A2 alleles (separately) for each population and write it in the last two columns. a) If we use the formula on the equation sheet that uses the number of alleles (which is double the number of perch): p Eramosa = (2*125+550)/2000 = 0.4 q Eramosa = 1-p = 0.6 p Speed River = (2*270+500)/2000 = 0.52 q Speed River = 1-p = 0.48 [b] Are these populations approximately in Hardy-Weinberg equilibrium? If they are not in HWE then which assumptions are likely being violated? For Eramosa under HWE expected genotype frequencies would be: p 2 2pq q 2 (0.4) 2 2(0.4)(0.6) (0.6) 2 0.16 0.48 0.36 We multiply these by the number of fish 1000 to get the number expected of each genotype: For the Eramosa River*: Chi squared, χ2 = 21.267 with 2 degrees of freedom. The two-tailed P value 0.0001. Very highly significant! Could there be selection for heterozygotes for this locus in the Eramosa River?
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- Subido en
- 3 de noviembre de 2023
- Número de páginas
- 10
- Escrito en
- 2023/2024
- Tipo
- Examen
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