Pharmacology NCLEX

Packed RBCs (administration of blood products) - - Time completed: 2-4 hours - Action/Use: increase available RBC, severe anemia, hemoglobinopathies, hemolytic anemia, erythroblastosis fetalis - Monitor for reaction: acute hemolytic, febrile, anaphylactic, mild allergic, and sepsis Platelets (administration of blood products) - - Time completed: 15-30 mins - Action/use: increase platelet count, active bleeding, thrombocytopenia, aplastic anemia, bone marrow suppression - Monitor for reaction: febrile and sepsis FFP (administration of blood products) - - Time completed: 30-60 minutes - Action/Use: Replace clotting factors (hemorrhage, burns, shock, thrombotic thrombocytopenic purpura (TP), reverse effects of warfarin) - Monitor for reaction: acute hemolytic, febrile, anaphylactic, mild allergic, hypervolemia, sepsis Pheresed granulocytes (administration of blood products) - - Time completed: 45-60 minutes - Action/Use: severe neutropenia, neonatal sepsis, neutrophil dysfunction - Monitor for reaction: acute hemolytic, febrile, anaphylactic, mild allergic, hypervolemia, sepsis Albumin (administration of blood products) - - Time completed: 5% (1-10 mL/min), 25% (4 mL/min) - Action/Use: expand volume via oncotic changes, hypovolemia, hypoalbuminemia, burns, severe nephrosis, hemolytic disease of the newborn - Monitor for reaction: risk for hyervolemia and pulmonary edema