NURS232 – Pharmacology 100% VERIFIED TEST SOLUTIONS 2023/2024

NURS232 – Pharmacology 100% VERIFIED TEST SOLUTIONS 2023/2024 The rate of dissolution helps determine... - ANSWER rate of absorption How does surface area affect absorption? - ANSWER the larger the surface area, the faster the absorption will be (this is why meds are usually absorbed in the small intestine due to the microvilli) How does blood flow affect absorption? - ANSWER drugs are absorbed faster where blood flow is high this is b/c blood containing newly absorbed drug will be rapidly replaced by drug free blood. This creates a concentration gradient between blood and outside of blood. therefore, Higher [] gradient = faster absorption. Why are lipid-soluble drugs absorbed more rapdidly? - ANSWER they can readily cross the membranes that separate them from the blood What is pH partitioning? - ANSWER the difference between the pH of plasma and pH at the site of administration when there is a pH gradient between two sides of a membrane, drug molecules tend to accumulate on th