Lippincott Pharmacology CNS questions with correct answers

Theophylline - Answer Methylxanthine (CNS stimulant) in tea Tx: 2nd line for asthma Theobromine - Answer Methylxanthine (CNS stimulant) in coccoa Inotropic - Answer Modifies the force or speed of contraction of muscles. Varenicline - Answer Chantix: smoking cessation Attenuates rewarding effects of nicotine AE: Suicidal thoughts, vivid nightmares Cocaine MOA - Answer Psychostimulant Blocks reuptake of norepi, 5HT + dopa, prolonging their actions. Chronic use depletes dopa receptors Amphetamine - Answer Adderal: psychomotor stimulant used to tx ADHD. Similar MOA to cocaine Dextroamphetamine - Answer Dexadrene Tx: attention span & can alleviate many of the behavioral problems associated with ADHD in addition to reducing hyperkinesia Lisdexamfetamine - Answer Vyvanse: prodrug -> converted to dextroamphetamine after GI absorption and metabolism Methylphenidate - Answer Ritalin: schedule 2 CNS-stimulant similar to amphetamine. Tx: ADHD & narcolepsy Blocks dopamine reuptake more than norepinephrine reuptake; may also increase their release. Atomoxetine - Answer Non-stimulant drug used to tx ADHD More selective for inhibition of norepinephrine reuptake.