PEBC Part I sample questions With Complete Solutions
1 Folic acid has tetrahydrofolate coenzyme activity which is
based on the:
a. pyrimidine ring.
b. purine ring.
c. pyrazine ring.
d. pteridine ring.
e. pyridine ring. correct answer: d
2 Enkephalins are peptides that:
a. have narcotic antagonist activity.
b. exert actions resembling those of opioids.
c. are found only in the central nervous system.
d. cause blood vessel wall relaxation.
e. transmit pain impulses. correct answer: b
3 β-Carotene is the precursor of:
a. retinol.
b. thiamine.
c. calciferol.
d. riboflavin.
e. retinoic acid correct answer: a
4 True statements regarding transcription include which of the
following?
a. The enzyme responsible for initiating transcription is RNA
polymerase.
b. The enzyme responsible for initiating transcription is DNA
polymerase.
,c. During transcription, the genetic information contained in the
nucleotide sequence
of tRNA is translated into a protein structure.
d. The process of transcription includes the splicing of exons.
e. Following initiation, the next stage of transcription is
termination. correct answer: a
5 Diphtheria is caused by:
a. Plasmodium.
b. Vibrio.
c. Shigella.
d. Neisseria.
e. Corynebacterium. correct answer: e
6 Which of the following blood vessels transports nutrient rich
blood from the intestines to the liver?
a. Hepatic artery
b. Hepatic portal vein
c. Great saphenous vein
d. Inferior vena cava
e. Superior vena cava correct answer: b
7 The blood volume of the average adult is approximately:
a. 5 L.
b. 10 L.
c. 15 L.
d. 20 L.
e. 25 L. correct answer: a
,8 In adults, community-acquired pneumonia caused by which of
the following organisms is associated with the highest mortality
rate?
a. Chlamydia pneumoniae
b. Mycoplasma pneumoniae
c. Haemophilus influenzae
d. Streptococcus pneumoniae
e. Pneumocystis jirovecii correct answer: d
9 Which of the following is the major inhibitory
neurotransmitter in the brain?
a. Gamma-aminobutyric acid
b. Dopamine
c. Glutamate
d. Acetylcholine
e. Glycine correct answer: a
10 Which of the following enzymes catalyzes the synthesis of
DNA from viral RNA?
a. Reverse transcriptase
b. DNA polymerase
c. RNA polymerase
d. Endonuclease
e. Aminoacyl-tRNA synthetase correct answer: a
11 Of the essential transition metal ions found in the human
body, the one present at highest overall concentration is:
a. copper.
b. cobalt.
c. iron.
, d. manganese.
e. zinc. correct answer: c
12 The optic disc is also called the:
a. blind spot.
b. cornea.
c. iris.
d. pupil.
e. macula lutea. correct answer: a
13 If systemic blood pressure decreases, which of the following
would occur to help return blood pressure to normal?
a. Increased urine production
b. Increased acetylcholine release
c. Increased aldosterone secretion
d. Increased diameter of systemic arterioles
e. Increased erythropoietin production correct answer: c
14 If the pKa of phenobarbital is 7.4, what approximate fraction
of the drug would be
ionized at pH 8.4?
a. 10%
b. 30%
c. 50%
d. 90%
e. 100% correct answer: d
15 All of the following statements concerning the lyophilization
of a parenteral product
are correct, EXCEPT:
a. there is minimal loss of activity in heat labile materials.
1 Folic acid has tetrahydrofolate coenzyme activity which is
based on the:
a. pyrimidine ring.
b. purine ring.
c. pyrazine ring.
d. pteridine ring.
e. pyridine ring. correct answer: d
2 Enkephalins are peptides that:
a. have narcotic antagonist activity.
b. exert actions resembling those of opioids.
c. are found only in the central nervous system.
d. cause blood vessel wall relaxation.
e. transmit pain impulses. correct answer: b
3 β-Carotene is the precursor of:
a. retinol.
b. thiamine.
c. calciferol.
d. riboflavin.
e. retinoic acid correct answer: a
4 True statements regarding transcription include which of the
following?
a. The enzyme responsible for initiating transcription is RNA
polymerase.
b. The enzyme responsible for initiating transcription is DNA
polymerase.
,c. During transcription, the genetic information contained in the
nucleotide sequence
of tRNA is translated into a protein structure.
d. The process of transcription includes the splicing of exons.
e. Following initiation, the next stage of transcription is
termination. correct answer: a
5 Diphtheria is caused by:
a. Plasmodium.
b. Vibrio.
c. Shigella.
d. Neisseria.
e. Corynebacterium. correct answer: e
6 Which of the following blood vessels transports nutrient rich
blood from the intestines to the liver?
a. Hepatic artery
b. Hepatic portal vein
c. Great saphenous vein
d. Inferior vena cava
e. Superior vena cava correct answer: b
7 The blood volume of the average adult is approximately:
a. 5 L.
b. 10 L.
c. 15 L.
d. 20 L.
e. 25 L. correct answer: a
,8 In adults, community-acquired pneumonia caused by which of
the following organisms is associated with the highest mortality
rate?
a. Chlamydia pneumoniae
b. Mycoplasma pneumoniae
c. Haemophilus influenzae
d. Streptococcus pneumoniae
e. Pneumocystis jirovecii correct answer: d
9 Which of the following is the major inhibitory
neurotransmitter in the brain?
a. Gamma-aminobutyric acid
b. Dopamine
c. Glutamate
d. Acetylcholine
e. Glycine correct answer: a
10 Which of the following enzymes catalyzes the synthesis of
DNA from viral RNA?
a. Reverse transcriptase
b. DNA polymerase
c. RNA polymerase
d. Endonuclease
e. Aminoacyl-tRNA synthetase correct answer: a
11 Of the essential transition metal ions found in the human
body, the one present at highest overall concentration is:
a. copper.
b. cobalt.
c. iron.
, d. manganese.
e. zinc. correct answer: c
12 The optic disc is also called the:
a. blind spot.
b. cornea.
c. iris.
d. pupil.
e. macula lutea. correct answer: a
13 If systemic blood pressure decreases, which of the following
would occur to help return blood pressure to normal?
a. Increased urine production
b. Increased acetylcholine release
c. Increased aldosterone secretion
d. Increased diameter of systemic arterioles
e. Increased erythropoietin production correct answer: c
14 If the pKa of phenobarbital is 7.4, what approximate fraction
of the drug would be
ionized at pH 8.4?
a. 10%
b. 30%
c. 50%
d. 90%
e. 100% correct answer: d
15 All of the following statements concerning the lyophilization
of a parenteral product
are correct, EXCEPT:
a. there is minimal loss of activity in heat labile materials.
