USMLE Step 1 Questions with Updated Answers (100% Verified)

USMLE Step 1 Questions with Updated Answers (100% Verified) Hormone to test for menopause. - CORRECT ANSWER high FSH Treatment of Heparin Induced Thrombocytopenia - CORRECT ANSWER Direct thrombin inhibitors-Agatroban Then protamine sulfate PT or PTT for Heparin - CORRECT ANSWER PTT PT or PTT for Warfarin - CORRECT ANSWER PT Skin necrosis from warfarin, what do you do? - CORRECT ANSWER Give heparin Antidote to excessive thrombolytics - CORRECT ANSWER Aminocaproic acid Glanzmanns Thrombasthenia - CORRECT ANSWER GPIIb/IIIa- platelet adhesion Bernard soulier - CORRECT ANSWER Gp1b Aspirin decreases platelet adehsion, activation or aggregation? - CORRECT ANSWER Activation Drugs that decrease platelet activation - CORRECT ANSWER aspirin, toclopidine, clopidogrel- block ADP receptors Drugs that decrease aggregation - CORRECT ANSWER abciximab, eptifibatide, tirofiban Why do sulfonamides decrease increase PT in patients on warfarin? - CORRECT ANSWER Sulfonamides displace the weakly but extensively bound warfarin on plasma proteins. This is different mechanism from cimetidine which increase P450 Onset, peak effect and duration of lispro - CORRECT ANSWER onset: 0.3-0.5hrs peak effect: 1-2 hrs duration: 2-4hrs Onset peak effect and duration of regular - CORRECT ANSWER onset: 0.5-1hrs peak effect: 2-4hrs duration: 5-7hrs