Dunphy Primary Care Hematological disorders questions with correct answers

Is polycythemia vera primary or secondary? - Answer Primary -- it is neoplastic proliferation of mature myeloid cells, mainly RBCs What do labs look like with polycythemia vera? - Answer Elevated RBC, HGB, HCT What gene mutation confirms diagnosis in 95% of cases of Polycythemia Vera? - Answer JAK2 V617 Secondary causes of polycythemia vera? - Answer Smoking, hypoxia, erythropoietin secreting cyst of tumor Does secondary polycythemia vera have splenomegaly? - Answer No What is the clinical presentation of Polycythemia Vera? - Answer -Median age of onset in 60 years old -More common in men -Expanded red cell volume -Symptoms develop SLOWLY, over time Does polycythemia vera cause RBC, HCT, and HGB to be too high or too low? - Answer Too high