AAMC FL 1 FULL REVIEW- Bio/Biochem | 60 Questions with 100% Correct Answers | Updated & Verified | 26 Pages

Based on the data presented in the passage, which statement best describes the HSP110ΔE9 allele? A.Cancer-promoting and dominant to HSP110WT B.Cancer-promoting and recessive to HSP110WT C.Cancer-suppressing and dominant to HSP110WT D.Cancer-suppressing and recessive to HSP110WT - ANS - Cross out A and B. LOOK AT THE FIGURE! Tumor volume is DOWN. Table 2 shows that HSP110ΔE9 allele when mixed with HSP110WT there is more apoptotic cells. So it's dominant. SLOW THE HECK DOWN AND READ Based on the passage, in MSI CRC primary tumor cells, the size of the deletion in the HSP110 T17 microsatellite is inversely correlated with: A.the amount of HSP110ΔE9 protein expressed. B.the number of mature HSP110WT transcripts synthesized. C.the frequency of the omission of HSP110 Exon 9 during splicing