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Samenvatting Overzicht AP2 - Geneeskunde bachelor jaar 1

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Overzicht AP2 - Geneeskunde bachelor jaar 1

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Uploaded on
February 2, 2023
Number of pages
3
Written in
2020/2021
Type
Summary

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Aandoeningen:
Nieren

Nefritisch syndroom

IgA-nefropathie - Productie van ‘verkeerd’ IgA door immuuncellen (B-cellen)
Groep:
- Mannen vaker aangedaan dan vrouwen
- Blanken/Aziaten vaker aangedaan dan negroïde patiënten
Symptomen:
- Bloed in urine → microscopische hematurie
- Pijn in flanken en in aanvallen
- Proteïnurie
Behandeling:
- Corticosteroïden
- Zout beperken
- Bloeddruk behandelen
- Cholesterol verlagen
- Visolie
- Stoppen met roken

Anti-GBM nefritis - Een probleem voor zowel de longen als de nieren
(Goodpasture) - Er wordt een antistof gemaakt tegen het collageen in het basaalmembraan.
Diagnostiek:
- Bloedingen gelokaliseerd in de alveoli
- Immunofluorescentie → antistoffen tegen de basaalmembraan opgespoord

Postinfectieuze Symptomen:
basaalmembraan - Macroscopische hematurie

Granulomatosis - Systeemziekte
met polyangiitis ← Groep:
ANCA - Mannen vaker aangedaan dan vrouwen
geassocieerde - Leeftijd vaak boven de 40
vasculitis - Vaker bij kaukasische patiënten dan bij negroïde patiënten.
Symptomen:
- Verminderde eetlust
- Koorts
- Spierklachten en gewrichtsklachten
Behandeling:
- Prednison + cyclofosfamide

SLE - Immuuncomplex nefritis
Groep:
- Vrouwen vaker aangedaan dan mannen
- Piekincidentie tussen 15-45 jaar
- Kaukasische patiënten minder aangedaan
Symptomen:
- Gewrichtsklachten
- Bloedneuzen
- Bloed ophoesten
Behandeling:
- Antibiotica
- Dialyse



Overzicht AP2 - Sofia Rabbanizadah
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