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Exam (elaborations)

Nursing Nephrotic Study Guide

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NUR 265 EXAM ONE STUDY GUIDE  Nephrotic Syndrome: o NS is a condition of increased glomerular permeability that allows larger molecules to pass through the membrane into the urine and then be excreted. o Immunological Kidney disorder o This causes massive loss of protein in the urine, edema formation, and decreased plasma albumin levels.  Proteinuria- severe protein loss more than 3.5 g in 24- hour urine sample. o Key features:  Massive proteinuria 3.5g / 24hrs  Hypoalbuminemia 3g/dL  Edema (facial and periorbital)  Lipiduria  Hyperlipidemia  Increased coagulation (renal vein thrombosis)  Reduced kidney function (↑ BUN, ↑ Cr, ↓ GFR)

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