ADVANCED PHARM EXAM 1 STUDY
GUIDE WITH ANSWERS
◉ Which drug class is replacing beta blockers as the "go to" post-
myocardial infarction (MI) medication?
A. Ca channel blockers
B. Central acting alpha blockers
C. Ace inhibitors
D. Newer generation aldosterone inhibitors
Answer: C. Ace inhibitors
◉ A 72 year old patient takes omeprazole for their chronic GERD.
Chronic long-term ompeprazole use places them at risk for?
A. Megaloblastic anemia
B. Loperamide four times a day throughout the trip
C. Hypertension
D. Strokes
Answer: A. Megaloblastic anemia
◉ Art is a 55-year-old smoker who has been diagnosed with angina
and placed on nitrates. He complains of headaches after using his
nitrate. An appropriate reply might be:
,A. "This is a parasympathetic response to the vasodilating effects of
the drug."
B. "Headaches are common side effects with these drugs. How
severe are they?"
C. "This is associated with your smoking. Let's work on having you
stop smoking."
D. "This is not related to your medication. Are you under a lot of
stress?"
Answer: B. "Headaches are common side effects with these drugs.
How severe are they?"
◉ Direct renin inhibitors have the following properties. They:
A. Are primarily generic drugs
B. Are a renin-angiotensin-aldosterone system (RAAS) medication
that is safe during pregnancy
C. Can be used with an angiotensin-converting enzyme and
angiotensin II receptor
blocker medications for stronger impact
D. "Shut down" the entire RAAS cycle
Answer: D. "Shut down" the entire RAAS cycle
◉ Dulcea has type 2 diabetes and a high triglyceride level. She has
gemfibrozil prescribed to treat her hypertriglyceridemia. A history
of which of the following might contraindicate the use of this drug?
A. Reactive airway disease/asthma
, B. Inflammatory bowel disease
C. Allergy to aspirin
D. Gallbladder disease
Answer: D. Gallbladder disease
◉ A potentially life-threatening adverse response to ACE inhibitors
is angioedema. Which of the following statements is true about this
adverse response?
A. Swelling of the tongue or hoarseness are the most common
symptoms.
B. It appears to be related to the decrease in aldosterone production.
C. Presence of a dry, hacky cough indicates a high risk for this
adverse response.
D. Because it takes time to build up a blood level, it occurs after
being on the drug for about 1 week.
Answer: A. Swelling of the tongue or hoarseness are the most
common symptoms.
◉ Angiotensin-converting enzyme inhibitors are the drug of choice
in treating hypertension in diabetic patients because they:
a. improve insulin sensitivity.
b. improve renal hemodynamics.
c. reduce the production of angiotensin II.
d. all of the above.
Answer: D. All of the above
GUIDE WITH ANSWERS
◉ Which drug class is replacing beta blockers as the "go to" post-
myocardial infarction (MI) medication?
A. Ca channel blockers
B. Central acting alpha blockers
C. Ace inhibitors
D. Newer generation aldosterone inhibitors
Answer: C. Ace inhibitors
◉ A 72 year old patient takes omeprazole for their chronic GERD.
Chronic long-term ompeprazole use places them at risk for?
A. Megaloblastic anemia
B. Loperamide four times a day throughout the trip
C. Hypertension
D. Strokes
Answer: A. Megaloblastic anemia
◉ Art is a 55-year-old smoker who has been diagnosed with angina
and placed on nitrates. He complains of headaches after using his
nitrate. An appropriate reply might be:
,A. "This is a parasympathetic response to the vasodilating effects of
the drug."
B. "Headaches are common side effects with these drugs. How
severe are they?"
C. "This is associated with your smoking. Let's work on having you
stop smoking."
D. "This is not related to your medication. Are you under a lot of
stress?"
Answer: B. "Headaches are common side effects with these drugs.
How severe are they?"
◉ Direct renin inhibitors have the following properties. They:
A. Are primarily generic drugs
B. Are a renin-angiotensin-aldosterone system (RAAS) medication
that is safe during pregnancy
C. Can be used with an angiotensin-converting enzyme and
angiotensin II receptor
blocker medications for stronger impact
D. "Shut down" the entire RAAS cycle
Answer: D. "Shut down" the entire RAAS cycle
◉ Dulcea has type 2 diabetes and a high triglyceride level. She has
gemfibrozil prescribed to treat her hypertriglyceridemia. A history
of which of the following might contraindicate the use of this drug?
A. Reactive airway disease/asthma
, B. Inflammatory bowel disease
C. Allergy to aspirin
D. Gallbladder disease
Answer: D. Gallbladder disease
◉ A potentially life-threatening adverse response to ACE inhibitors
is angioedema. Which of the following statements is true about this
adverse response?
A. Swelling of the tongue or hoarseness are the most common
symptoms.
B. It appears to be related to the decrease in aldosterone production.
C. Presence of a dry, hacky cough indicates a high risk for this
adverse response.
D. Because it takes time to build up a blood level, it occurs after
being on the drug for about 1 week.
Answer: A. Swelling of the tongue or hoarseness are the most
common symptoms.
◉ Angiotensin-converting enzyme inhibitors are the drug of choice
in treating hypertension in diabetic patients because they:
a. improve insulin sensitivity.
b. improve renal hemodynamics.
c. reduce the production of angiotensin II.
d. all of the above.
Answer: D. All of the above