IHC
Question 1.
_________________ is the process of detecting antigens (proteins) in a cells of tissue selection using a Ag/Ab reaction tagged with a
visible label
ANSWER
Immunohistochemistry (IHC)
Question 2.
IHC combines what 3 techniques
ANSWER
Histological Immunological Biochemical
Question 3.
Anything that causes an immune response in animals /humans and stimulates the production of anti-bodies in the host =
________________
ANSWER
Immunogen
Question 4.
A protein produced by plasma cells as a result of an immunogen = _________________
ANSWER
Antibody
Question 5.
What cell produces antibodies?
ANSWER
Plasma cell
Question 6.
_____________________ = a protein biomarker used in the identification & classification of cells. They trigger the production of
immunoglobulins
ANSWER
Antigens
Question 7.
________________ _____________ = this process helps recover masked epitopes by breaking aldehyde bonds.
ANSWER
Androgen retrieval (Heat induced epitope re-trieval) (Epitope is the part of an antigen that is recognized by the immune system - specifically by the
antibodies )
, Question 8.
A ______________ is also known as an immunoglobulin
ANSWER
Antibody
Question 9.
An antibody is a large ____ shaped protein produced by plasma cells
ANSWER
Y shaped protein
Question 10.
What are used by the immune system to identify and neutralize foreign objects?
ANSWER
Antibodies
Question 11.
An antibody recognizes an _____________
ANSWER
Antigen (which is a unique part of the foreign target)
Question 12.
For IHC detection antibodies are classified as either ____________ or __________ reagents
ANSWER
Primary or secondary reagents
Question 13.
______________ antibodies are raised against the antigen of interest and are typically unconjugated (unlabeled)
ANSWER
Primary antibodies
Question 14.
_____________ antibodies are raised against immunoglobulins of the primary antibody species
ANSWER
Secondary antibodies
Question 15.
4 parts of an antibody
ANSWER
Heavy chain Light chain Variable region Constant region
Question 1.
_________________ is the process of detecting antigens (proteins) in a cells of tissue selection using a Ag/Ab reaction tagged with a
visible label
ANSWER
Immunohistochemistry (IHC)
Question 2.
IHC combines what 3 techniques
ANSWER
Histological Immunological Biochemical
Question 3.
Anything that causes an immune response in animals /humans and stimulates the production of anti-bodies in the host =
________________
ANSWER
Immunogen
Question 4.
A protein produced by plasma cells as a result of an immunogen = _________________
ANSWER
Antibody
Question 5.
What cell produces antibodies?
ANSWER
Plasma cell
Question 6.
_____________________ = a protein biomarker used in the identification & classification of cells. They trigger the production of
immunoglobulins
ANSWER
Antigens
Question 7.
________________ _____________ = this process helps recover masked epitopes by breaking aldehyde bonds.
ANSWER
Androgen retrieval (Heat induced epitope re-trieval) (Epitope is the part of an antigen that is recognized by the immune system - specifically by the
antibodies )
, Question 8.
A ______________ is also known as an immunoglobulin
ANSWER
Antibody
Question 9.
An antibody is a large ____ shaped protein produced by plasma cells
ANSWER
Y shaped protein
Question 10.
What are used by the immune system to identify and neutralize foreign objects?
ANSWER
Antibodies
Question 11.
An antibody recognizes an _____________
ANSWER
Antigen (which is a unique part of the foreign target)
Question 12.
For IHC detection antibodies are classified as either ____________ or __________ reagents
ANSWER
Primary or secondary reagents
Question 13.
______________ antibodies are raised against the antigen of interest and are typically unconjugated (unlabeled)
ANSWER
Primary antibodies
Question 14.
_____________ antibodies are raised against immunoglobulins of the primary antibody species
ANSWER
Secondary antibodies
Question 15.
4 parts of an antibody
ANSWER
Heavy chain Light chain Variable region Constant region
