PHM 421 - Final Exam Questions &
Answers17
What is the boxed warning for the product shown below (AndroGel)?
A) Sleep apnea
B) Venous thromboembolism (VTE)
C) Edema with or without congestive heart failure (CHF)
D) Secondary exposure to testosterone in children can occur, resulting in virilization
E) An increase in prostate-specific antigen (PSA) - ANSWERS-D
A compounding pharmacist is considering using poloxamer gel in his pharmacy. Which of the
following statements concerning poloxamer gel is INCORRECT?
A) It is a liquid when stored cold and forms a gel when stored at room temperature
B) It has both a hydrophobic and a hydrophilic component
C) It is commonly used for compounding transdermal products
D) It is thermoreversible
E) It is a liquid at room temperature and forms a gel when cold - ANSWERS-E
Regarding the PLO gel, the P, L, & O stand for which of the following, respectively?
A) P for Poloxamer (Pluronic), L for Lecithin, & O for Olive Oil
B) P for Poloxamer (Pluronic), L for Lecithin, & O for Organogel
C) P for Poloxamer (Pluronic), L for Liquid, & O for Oil
,D) P for Polymer, L for Lecithin, & O for Oil
E) P for Poloxamer (Pluronic), L for Lecithin, & O for Oil - ANSWERS-E
Which of the following is correct regarding gels & magmas? Select all that apply.
A) Gels are semisolid systems consisting of dispersions of small or large molecules in an aqueous
liquid vehicle rendered jellylike by the addition of a gelling agent
B) If the gel has small, discrete particles in it, it is classified as a two-phase system, which if also
called a magma
C) Magma is a single-phase gel
D) Carbomer is a synthetic gelling agent that gives a gel structure at a pH value > 6
E) Milk of magnesia is an example of a magma - ANSWERS-A, B, D, E
Regarding the topical treatment of acne with tretinoin. Select all that apply.
A) It is within the 1st-line treatment for mild, moderate, and severe acne
B) Retinoids are teratogenic
C) Tretinoin is available as an oral dosage form, while isotretinoin is available as a topical
D) Adapalene is a retinoid
E) Differin Gel 0.3% is available as an OTC
F) Retin-A Micro is formulated using the Microsponge system, an acrylate-based system for the
inclusion of the active in an aqueous gel and for slow release, thereby reducing skin irritation
G) Benzoyl peroxide is available in 2-in-1 and 3-in-1 topical gel formulations along with
adapalene and clindamycin respectively
H) Retin-A gel is available in higher strengths than Retin-A Micro gel
I) Carbomer is a gelling agent used in many retinoid topical gels, and it requires an acidic
condition to function - ANSWERS-A, B, D, F, G
, A patient has a sulfa allergy. Which of the following medications is contraindicated in this
patient? Select all that apply
A) Trusopt
B) Xalatan
C) Cosopt
D) Restasis
E) Lumigan - ANSWERS-A, C
Choose the correct counseling statement that a pharmacist should provide to a patient
beginning prostaglandin analog therapy for glaucoma
A) The dose should be administered in the morning
B) Blood work will be needed to check that the drug is working
C) It must be administered at night because it can make you very tired
D) If using Xalatan, the patient should administer three times daily
E) Eyelash growth and darkening of the iris may occur - ANSWERS-E
Rx: Ofloxacin 0.3%
Sig: Place 1 drop OU BID for 10 days
Based on the instructions given in the prescription, where should the drops be placed?
A) Right eye
B) Left eye
C) Right ear
D) Left ear
Answers17
What is the boxed warning for the product shown below (AndroGel)?
A) Sleep apnea
B) Venous thromboembolism (VTE)
C) Edema with or without congestive heart failure (CHF)
D) Secondary exposure to testosterone in children can occur, resulting in virilization
E) An increase in prostate-specific antigen (PSA) - ANSWERS-D
A compounding pharmacist is considering using poloxamer gel in his pharmacy. Which of the
following statements concerning poloxamer gel is INCORRECT?
A) It is a liquid when stored cold and forms a gel when stored at room temperature
B) It has both a hydrophobic and a hydrophilic component
C) It is commonly used for compounding transdermal products
D) It is thermoreversible
E) It is a liquid at room temperature and forms a gel when cold - ANSWERS-E
Regarding the PLO gel, the P, L, & O stand for which of the following, respectively?
A) P for Poloxamer (Pluronic), L for Lecithin, & O for Olive Oil
B) P for Poloxamer (Pluronic), L for Lecithin, & O for Organogel
C) P for Poloxamer (Pluronic), L for Liquid, & O for Oil
,D) P for Polymer, L for Lecithin, & O for Oil
E) P for Poloxamer (Pluronic), L for Lecithin, & O for Oil - ANSWERS-E
Which of the following is correct regarding gels & magmas? Select all that apply.
A) Gels are semisolid systems consisting of dispersions of small or large molecules in an aqueous
liquid vehicle rendered jellylike by the addition of a gelling agent
B) If the gel has small, discrete particles in it, it is classified as a two-phase system, which if also
called a magma
C) Magma is a single-phase gel
D) Carbomer is a synthetic gelling agent that gives a gel structure at a pH value > 6
E) Milk of magnesia is an example of a magma - ANSWERS-A, B, D, E
Regarding the topical treatment of acne with tretinoin. Select all that apply.
A) It is within the 1st-line treatment for mild, moderate, and severe acne
B) Retinoids are teratogenic
C) Tretinoin is available as an oral dosage form, while isotretinoin is available as a topical
D) Adapalene is a retinoid
E) Differin Gel 0.3% is available as an OTC
F) Retin-A Micro is formulated using the Microsponge system, an acrylate-based system for the
inclusion of the active in an aqueous gel and for slow release, thereby reducing skin irritation
G) Benzoyl peroxide is available in 2-in-1 and 3-in-1 topical gel formulations along with
adapalene and clindamycin respectively
H) Retin-A gel is available in higher strengths than Retin-A Micro gel
I) Carbomer is a gelling agent used in many retinoid topical gels, and it requires an acidic
condition to function - ANSWERS-A, B, D, F, G
, A patient has a sulfa allergy. Which of the following medications is contraindicated in this
patient? Select all that apply
A) Trusopt
B) Xalatan
C) Cosopt
D) Restasis
E) Lumigan - ANSWERS-A, C
Choose the correct counseling statement that a pharmacist should provide to a patient
beginning prostaglandin analog therapy for glaucoma
A) The dose should be administered in the morning
B) Blood work will be needed to check that the drug is working
C) It must be administered at night because it can make you very tired
D) If using Xalatan, the patient should administer three times daily
E) Eyelash growth and darkening of the iris may occur - ANSWERS-E
Rx: Ofloxacin 0.3%
Sig: Place 1 drop OU BID for 10 days
Based on the instructions given in the prescription, where should the drops be placed?
A) Right eye
B) Left eye
C) Right ear
D) Left ear
