NURS660 Psychopharm 660 Exam 1 UPDATED ACTUAL
QUESTIONS WITH CORRECT ANSWERS
Question 1.
Positive Symptoms of Schizophrenia
ANSWER
Delusions, hallucinations, distortions, agitation, disorganized speech, disorganized behavior
Question 2.
Where do positive symptoms originate?
ANSWER
Mesolimbic dopamine pathway
Question 3.
Medications to treat positive symptoms
ANSWER
Antipsychotics
Question 4.
Negative symptoms of schizophrenia
ANSWER
Flat affect, alogia, affective blunting, asociality, anhedonia, avolition.
Question 5.
Where do negative symptoms originate?
ANSWER
Mesocortical dopamine pathway. May also involve mesolimbic regions such as nucleus
accumbens
, Question 6.
Medications to treat negative symptoms
ANSWER
Vraylar, amisulpride
Question 7.
Hypotheses of Schizophrenia
ANSWER
-Mesolimbic pathway is hypothesized to be hyperactive resulting in excess dopamine at the
synapse.
-The gluatamate activity at NMDA receptors is hypofunctional
Question 8.
Mesolimbic Pathway Theory of Schizophrenia
ANSWER
Mesolimbic pathway is hyperactive, resulting in excess dopamine at the synapse which leads to
positive symptoms. Hyperactivity of mesolimbic dopamine neurons may also play a role in
aggression and hostile symptoms.
Question 9.
Five Different Dopamine Pathways in the brain
ANSWER
-Nigrostriatal Dopamine Pathway
-Mesolimbic dopamine pathway
-Mesocorticol dopamine pathway
-Tuberoinfundibular dopamine pathway
-Thalamic dopamine pathway
QUESTIONS WITH CORRECT ANSWERS
Question 1.
Positive Symptoms of Schizophrenia
ANSWER
Delusions, hallucinations, distortions, agitation, disorganized speech, disorganized behavior
Question 2.
Where do positive symptoms originate?
ANSWER
Mesolimbic dopamine pathway
Question 3.
Medications to treat positive symptoms
ANSWER
Antipsychotics
Question 4.
Negative symptoms of schizophrenia
ANSWER
Flat affect, alogia, affective blunting, asociality, anhedonia, avolition.
Question 5.
Where do negative symptoms originate?
ANSWER
Mesocortical dopamine pathway. May also involve mesolimbic regions such as nucleus
accumbens
, Question 6.
Medications to treat negative symptoms
ANSWER
Vraylar, amisulpride
Question 7.
Hypotheses of Schizophrenia
ANSWER
-Mesolimbic pathway is hypothesized to be hyperactive resulting in excess dopamine at the
synapse.
-The gluatamate activity at NMDA receptors is hypofunctional
Question 8.
Mesolimbic Pathway Theory of Schizophrenia
ANSWER
Mesolimbic pathway is hyperactive, resulting in excess dopamine at the synapse which leads to
positive symptoms. Hyperactivity of mesolimbic dopamine neurons may also play a role in
aggression and hostile symptoms.
Question 9.
Five Different Dopamine Pathways in the brain
ANSWER
-Nigrostriatal Dopamine Pathway
-Mesolimbic dopamine pathway
-Mesocorticol dopamine pathway
-Tuberoinfundibular dopamine pathway
-Thalamic dopamine pathway