WEEK 5 - NR 566 STUDYGUIDE QUESTIONS AND CORRECT ANSWERS
Question:
1. H1 antagonists, aka _______________ have 1st gen and 2nd gen meds: 1st gen: "ramines";
______________, chlorpheniramine, promethazine 2nd gen: ______________, cetirizine and
________________
Answer:
antihistamines diphenhydramine loratadine; fexofenadine
Question:
2. What is the most common side effect for 1st gen antihistamines? SE: N/V/D constipation,
___________ appetite, and anticholinergic effects list what pts should be mindful of when
taking it
Answer:
sedation decreased be mindful when driving, avoid alcohol and other CNS depressants!- can
intensify depressant effects of H1 antagonist. Take with meals to decrease N/V
Question:
3. list anticholinergic side effects: ____ mouth, urinary retention and hesitation and
___________
Answer:
dry constipation
Question:
4. 2nd gen antihistamines have little to no sedative effect, true or false? some side effects
are: dizziness, ______________, and ___________ especially in old people!
Answer:
true! incoordination, confusion
Question:
5. ___ generation antihistamines are the least anticholinergic, helpful in pts with BPH, urinary
retention and gastroparesis
Answer:
2nd
Question:
6. ____________ causes severe respiratory depression in young adults, contraindicated in kids
< 2 y/o
Answer:
promethazine
Question:
7. medication at _________ or use _____ generation med instead!
, Answer:
night 2nd
Question:
8. all H1 antagonists are useful for allergic disorder tx, true or false?
Answer:
true!
Question:
9. what H1 antagonists can be used for motion sickness?
Answer:
dimenhydramine, promethazine they block receptors on neuronal pathways leading to vestibular
apparatus of inner ear to vomiting center in medulla
Question:
10. all OTC sleep aids contain ___ gen H1 antagonists. ex: ______________ tolerance to
sedative effect occurs _________
Answer:
1st diphenhydramine quickly
Question:
11. _____________ and promethazine are contraindicated in kids <2 y/o, can cause death!
avoid __________ in pregnancy _____ generation antihistamines are in Beers Criteria, avoid
giving to old heads!
Answer:
carbinoxamine antihistamines 1ST small doses of antihistamines do NOT cause sedation in infant,
safe to take while breastfeeding
Question:
12. if antihistamines are needed, give ____________ dose first can make ____ and glaucoma
worse
Answer:
smallest BPH
Question:
13. __ generation antihistamines cause CNS depression, most prominent with promethazine
and least with ___________________
Answer:
1st chlorpheniramine
Question:
14. ___ generation have more anticholinergic SE: dry mouth, urinary __________ and
_________, constipation ___ generation poorly crosses the BBB, low affinity for H1 receptors
Answer:
Question:
1. H1 antagonists, aka _______________ have 1st gen and 2nd gen meds: 1st gen: "ramines";
______________, chlorpheniramine, promethazine 2nd gen: ______________, cetirizine and
________________
Answer:
antihistamines diphenhydramine loratadine; fexofenadine
Question:
2. What is the most common side effect for 1st gen antihistamines? SE: N/V/D constipation,
___________ appetite, and anticholinergic effects list what pts should be mindful of when
taking it
Answer:
sedation decreased be mindful when driving, avoid alcohol and other CNS depressants!- can
intensify depressant effects of H1 antagonist. Take with meals to decrease N/V
Question:
3. list anticholinergic side effects: ____ mouth, urinary retention and hesitation and
___________
Answer:
dry constipation
Question:
4. 2nd gen antihistamines have little to no sedative effect, true or false? some side effects
are: dizziness, ______________, and ___________ especially in old people!
Answer:
true! incoordination, confusion
Question:
5. ___ generation antihistamines are the least anticholinergic, helpful in pts with BPH, urinary
retention and gastroparesis
Answer:
2nd
Question:
6. ____________ causes severe respiratory depression in young adults, contraindicated in kids
< 2 y/o
Answer:
promethazine
Question:
7. medication at _________ or use _____ generation med instead!
, Answer:
night 2nd
Question:
8. all H1 antagonists are useful for allergic disorder tx, true or false?
Answer:
true!
Question:
9. what H1 antagonists can be used for motion sickness?
Answer:
dimenhydramine, promethazine they block receptors on neuronal pathways leading to vestibular
apparatus of inner ear to vomiting center in medulla
Question:
10. all OTC sleep aids contain ___ gen H1 antagonists. ex: ______________ tolerance to
sedative effect occurs _________
Answer:
1st diphenhydramine quickly
Question:
11. _____________ and promethazine are contraindicated in kids <2 y/o, can cause death!
avoid __________ in pregnancy _____ generation antihistamines are in Beers Criteria, avoid
giving to old heads!
Answer:
carbinoxamine antihistamines 1ST small doses of antihistamines do NOT cause sedation in infant,
safe to take while breastfeeding
Question:
12. if antihistamines are needed, give ____________ dose first can make ____ and glaucoma
worse
Answer:
smallest BPH
Question:
13. __ generation antihistamines cause CNS depression, most prominent with promethazine
and least with ___________________
Answer:
1st chlorpheniramine
Question:
14. ___ generation have more anticholinergic SE: dry mouth, urinary __________ and
_________, constipation ___ generation poorly crosses the BBB, low affinity for H1 receptors
Answer:
