NCLEX RN Patient Safety Practice
Exam 100 Questions And Correct
Answers (Verified Answers) Plus
Rationales 2026
Question 1
A nurse is preparing to administer medication to a client. Which action is most
important for preventing a medication error?
A. Ask the client about allergies after administering the medication
B. Compare the medication label with the medication administration record
three times
C. Document the medication before giving it
D. Ask another nurse to administer all medications
Answer: B. Compare the medication label with the medication administration
record three times
Rationale: Comparing the medication label with the medication
administration record during preparation and administration helps verify the
correct medication, dose, route, and timing and reduces medication errors.
Question 2
Which client should the nurse identify as having the highest risk for falling?
A. A 25-year-old client with a wrist fracture
B. A 40-year-old client receiving oral antibiotics
C. An 82-year-old client receiving a sedative
D. A 35-year-old client with controlled hypertension
Answer: C. An 82-year-old client receiving a sedative
,Rationale: Older adults receiving sedating medications are at increased risk
for impaired balance, confusion, and falls. Fall precautions should be
implemented.
Question 3
A nurse finds a client lying on the floor beside the bed. What should the nurse
do first?
A. Help the client back into bed
B. Complete an incident report
C. Assess the client for injury
D. Notify the family
Answer: C. Assess the client for injury
Rationale: The nurse's immediate priority is assessing the client's airway,
circulation, level of consciousness, and possible injuries before moving the
client.
Question 4
Which intervention is appropriate when caring for a client at high risk for falls?
A. Keep all four side rails raised
B. Place the bed in the lowest position
C. Keep the room completely dark
D. Encourage the client to walk independently
Answer: B. Place the bed in the lowest position
Rationale: A low bed reduces the distance a client could fall. Additional
measures include keeping the call light within reach, maintaining a clear
environment, and providing assistance with ambulation.
Question 5
,A nurse is caring for a client who is confused and attempting to climb out of
bed. Which intervention should the nurse implement first?
A. Apply wrist restraints
B. Request a sedative prescription
C. Determine and address the cause of the agitation
D. Raise all four side rails
Answer: C. Determine and address the cause of the agitation
Rationale: Reversible causes such as pain, hypoxia, urinary retention,
medication effects, or delirium should be assessed and treated before
restraints or sedation are considered.
Question 6
Which action best prevents the transmission of infection between clients?
A. Wearing gloves for every client interaction
B. Performing hand hygiene before and after client contact
C. Wearing a gown when entering every room
D. Using sterile technique for routine care
Answer: B. Performing hand hygiene before and after client contact
Rationale: Hand hygiene is one of the most effective measures for preventing
transmission of microorganisms in healthcare settings.
Question 7
A nurse is caring for a client with suspected tuberculosis. Which personal
protective equipment is required?
A. Surgical mask
B. N95 respirator
C. Sterile gloves
D. Face shield only
Answer: B. N95 respirator
, Rationale: Tuberculosis requires airborne precautions. A fit-tested N95
respirator or equivalent respirator is used to protect healthcare personnel
from airborne particles.
Question 8
A nurse receives a verbal prescription that sounds unclear. What is the safest
action?
A. Administer the medication based on the nurse's interpretation
B. Ask another nurse what the prescription means
C. Clarify the prescription with the prescribing provider
D. Document that the provider gave an unclear order
Answer: C. Clarify the prescription with the prescribing provider
Rationale: Unclear prescriptions must be clarified before implementation.
Guessing can result in a serious medication error.
Question 9
Which client identification method is safest before administering medication?
A. Room number and diagnosis
B. Client's appearance and room number
C. Two approved client identifiers
D. Asking a family member to identify the client
Answer: C. Two approved client identifiers
Rationale: Using two approved identifiers, such as name and date of birth,
helps prevent wrong-client errors. Room number should not be used as an
identifier.
Question 10
A client is prescribed a medication to which the client reports a severe allergy.
What should the nurse do?
Exam 100 Questions And Correct
Answers (Verified Answers) Plus
Rationales 2026
Question 1
A nurse is preparing to administer medication to a client. Which action is most
important for preventing a medication error?
A. Ask the client about allergies after administering the medication
B. Compare the medication label with the medication administration record
three times
C. Document the medication before giving it
D. Ask another nurse to administer all medications
Answer: B. Compare the medication label with the medication administration
record three times
Rationale: Comparing the medication label with the medication
administration record during preparation and administration helps verify the
correct medication, dose, route, and timing and reduces medication errors.
Question 2
Which client should the nurse identify as having the highest risk for falling?
A. A 25-year-old client with a wrist fracture
B. A 40-year-old client receiving oral antibiotics
C. An 82-year-old client receiving a sedative
D. A 35-year-old client with controlled hypertension
Answer: C. An 82-year-old client receiving a sedative
,Rationale: Older adults receiving sedating medications are at increased risk
for impaired balance, confusion, and falls. Fall precautions should be
implemented.
Question 3
A nurse finds a client lying on the floor beside the bed. What should the nurse
do first?
A. Help the client back into bed
B. Complete an incident report
C. Assess the client for injury
D. Notify the family
Answer: C. Assess the client for injury
Rationale: The nurse's immediate priority is assessing the client's airway,
circulation, level of consciousness, and possible injuries before moving the
client.
Question 4
Which intervention is appropriate when caring for a client at high risk for falls?
A. Keep all four side rails raised
B. Place the bed in the lowest position
C. Keep the room completely dark
D. Encourage the client to walk independently
Answer: B. Place the bed in the lowest position
Rationale: A low bed reduces the distance a client could fall. Additional
measures include keeping the call light within reach, maintaining a clear
environment, and providing assistance with ambulation.
Question 5
,A nurse is caring for a client who is confused and attempting to climb out of
bed. Which intervention should the nurse implement first?
A. Apply wrist restraints
B. Request a sedative prescription
C. Determine and address the cause of the agitation
D. Raise all four side rails
Answer: C. Determine and address the cause of the agitation
Rationale: Reversible causes such as pain, hypoxia, urinary retention,
medication effects, or delirium should be assessed and treated before
restraints or sedation are considered.
Question 6
Which action best prevents the transmission of infection between clients?
A. Wearing gloves for every client interaction
B. Performing hand hygiene before and after client contact
C. Wearing a gown when entering every room
D. Using sterile technique for routine care
Answer: B. Performing hand hygiene before and after client contact
Rationale: Hand hygiene is one of the most effective measures for preventing
transmission of microorganisms in healthcare settings.
Question 7
A nurse is caring for a client with suspected tuberculosis. Which personal
protective equipment is required?
A. Surgical mask
B. N95 respirator
C. Sterile gloves
D. Face shield only
Answer: B. N95 respirator
, Rationale: Tuberculosis requires airborne precautions. A fit-tested N95
respirator or equivalent respirator is used to protect healthcare personnel
from airborne particles.
Question 8
A nurse receives a verbal prescription that sounds unclear. What is the safest
action?
A. Administer the medication based on the nurse's interpretation
B. Ask another nurse what the prescription means
C. Clarify the prescription with the prescribing provider
D. Document that the provider gave an unclear order
Answer: C. Clarify the prescription with the prescribing provider
Rationale: Unclear prescriptions must be clarified before implementation.
Guessing can result in a serious medication error.
Question 9
Which client identification method is safest before administering medication?
A. Room number and diagnosis
B. Client's appearance and room number
C. Two approved client identifiers
D. Asking a family member to identify the client
Answer: C. Two approved client identifiers
Rationale: Using two approved identifiers, such as name and date of birth,
helps prevent wrong-client errors. Room number should not be used as an
identifier.
Question 10
A client is prescribed a medication to which the client reports a severe allergy.
What should the nurse do?
