PORTAGE BIOD 210
GENETICS MODULE 7
EXAM WITH ACTUAL
ANSWERS
, proliferation - correct ans:abnormal growth and division
metastasis - correct ans:defects in the restraints that keep them localized to
a certain part of the body
tumor - correct ans:growth of a mass
benign - correct ans:tumor that is confined to a region
malignant - correct ans:cancerous tumor
Phildelphia chromosome - correct ans:implicated in chronic leukemias (CML)
translocation btw chromosomes 9 and 22
BCR-ABL fusion gene encoding for a tyrosine kinase that drives the growth of
CML cells
driver mutations - correct ans:impart some sort of growth advantage to the
cell that allow it to proliferate and spread
passenger mutations - correct ans:have no direct contribution to cancer
phenotype
stem cells - correct ans:undifferentiated cells
tumorigenesis - correct ans:development of a malignant tumor
polpy or adenoma - correct ans:small cluster of cells that are deective for a
gene call APC
GENETICS MODULE 7
EXAM WITH ACTUAL
ANSWERS
, proliferation - correct ans:abnormal growth and division
metastasis - correct ans:defects in the restraints that keep them localized to
a certain part of the body
tumor - correct ans:growth of a mass
benign - correct ans:tumor that is confined to a region
malignant - correct ans:cancerous tumor
Phildelphia chromosome - correct ans:implicated in chronic leukemias (CML)
translocation btw chromosomes 9 and 22
BCR-ABL fusion gene encoding for a tyrosine kinase that drives the growth of
CML cells
driver mutations - correct ans:impart some sort of growth advantage to the
cell that allow it to proliferate and spread
passenger mutations - correct ans:have no direct contribution to cancer
phenotype
stem cells - correct ans:undifferentiated cells
tumorigenesis - correct ans:development of a malignant tumor
polpy or adenoma - correct ans:small cluster of cells that are deective for a
gene call APC
