GENETICS EXAM 2 ESSENTIAL STUDY
QUESTIONS AND ANSWERS
◉ interference.
Answer: A measure of the independence of crossovers from each
other, calculated by subtracting the coefficient of coincidence from 1
◉ coefficient of coincidence.
Answer: ratio of observed double crossovers to expected double
crossovers
◉ mapping function.
Answer: Relates recombination frequencies to actual physical
distances between genes
◉ LOD scoring.
Answer: a statistical test often used for linkage analysis in human,
animal, and plant populations
◉ genetic linkage.
Answer: tendency for alleles of genes on the same chromosome to
be inherited together
, ◉ linkage analysis.
Answer: Gene mapping based on the detection of physical linkage
between genes, as measured by the rate of recombination, in
progeny from a cross
◉ haplotype.
Answer: A group of alleles of different genes on a single
chromosome that are closely enough linked to be inherited usually
as a unit
◉ single nucleotide polymorphism.
Answer: variation in a DNA sequence occurring when a single
nucleotide in a genome is altered
◉ deletion mapping.
Answer: Technique for determining the chromosomal location of a
gene by studying the association of its phenotype or product with
particular chromosome deletions
◉ chromosome duplication.
Answer: Mutation that doubles a segment of a chromosome.
◉ tandem duplication.
QUESTIONS AND ANSWERS
◉ interference.
Answer: A measure of the independence of crossovers from each
other, calculated by subtracting the coefficient of coincidence from 1
◉ coefficient of coincidence.
Answer: ratio of observed double crossovers to expected double
crossovers
◉ mapping function.
Answer: Relates recombination frequencies to actual physical
distances between genes
◉ LOD scoring.
Answer: a statistical test often used for linkage analysis in human,
animal, and plant populations
◉ genetic linkage.
Answer: tendency for alleles of genes on the same chromosome to
be inherited together
, ◉ linkage analysis.
Answer: Gene mapping based on the detection of physical linkage
between genes, as measured by the rate of recombination, in
progeny from a cross
◉ haplotype.
Answer: A group of alleles of different genes on a single
chromosome that are closely enough linked to be inherited usually
as a unit
◉ single nucleotide polymorphism.
Answer: variation in a DNA sequence occurring when a single
nucleotide in a genome is altered
◉ deletion mapping.
Answer: Technique for determining the chromosomal location of a
gene by studying the association of its phenotype or product with
particular chromosome deletions
◉ chromosome duplication.
Answer: Mutation that doubles a segment of a chromosome.
◉ tandem duplication.
