LATEST UPDATE 2026
*Canalicular Period* - Answers bronchi duplicate and become larger, Highly
vascular. 24w
Lumina of bronchi and the terminal bronchioles become larger and lung tissue
becomes ______________. - Answers Highly vascular.
_____ weeks: primordial alveolar ducts (terminal sacs): - Answers 24.
________ possible by end of this stage (lung tissue well vascularized). - Answers
Respiration. Canalicular period 24
24-26 weeker may survive if given intense care, but die d/t __________ and other
system immaturity. - Answers Respiratory.
*Terminal Saccular Period* - Answers Epithelium of terminal sacs thin and connect
with endothelial. Capilaries bulge into sacs. 26wk
Type I and II pheumocytes
More terminal sacs develop and their __________ becomes very thin. - Answers
Epithelium.
__________ begin to bulge into sacs. - Answers Capillaries. Terminal sac
Contact between ___________ and __________ cells establishes blood-air barrier,
which permits adequate gas exchange. - Answers Epithelial and endothelial.
Terminal sac
______ weeks: terminal sacs lined by squamous epithelial cells of endodermal origin.
- Answers 26. terminal sac
Type I pneumocytes: - Answers Across which gas exchange occurs. develop in
terminal sac period
Type II pneumocytes: - Answers Secrete pulmonary surfactant. terminal sac
Surfactant: - Answers - Facilitates expansion of terminal sacs.
- Production varies in fetuses of different ages.
- Begins by 20-22 weeks.
- Present in small amounts in premature infants.
- Reaches adequate amount in late fetal period.
- Antenatal corticosteroids and postnatal surfactant replacement therapy increase
survival rate.
, *Alveolar Period* - Answers 8m-3 years. mature aveoli forming, transition to
autonomous gas exchange
Thinned walled terminal sacs (future alveolar ducts) separated by _______________.
- Answers Loose connective tissue. aveolar period
Alveolocapillary membrane thin enough to allow ______ exchange. - Answers Gas.
aveolar period
Transition from placental gas exchange to __________ gas exchange: - Answers
Autonomous. aveolar period
Autonomous gas exchange: - Answers - Production of surfactant in alveolar sacs.
- Transformation of lungs into gas-exchanging organs.
- Establishment of parallel pulmonary and systemic circulations.
____% of mature alveoli develop in postnatal period. - Answers 95. aveolar period
Alveolar development largely complete by _______ of age. - Answers 3 years.
Fetal breathing movements occur before birth: - Answers - Cause aspiration of some
amniotic fluid into lungs.
- Movement stimulate lung development.
- Breathing movement increase as delivery approaches.
Look at the phenomena that stimulates the neonate to take his/her first breath.
Differentiate between the biochemical and mechanical events. - Answers
*Biochemical* - Answers
Relative hypoxia at end of labor and physical stimuli, such as cold, gravity, pain,
light, noise cause: - Answers Excitation of respiratory center.
Release of ________ pressure at birth may help stimulation. - Answers Thoracic.
Squeezing of thorax in last minute of second stage labor, in birth canal help to: -
Answers Extrude some upper airway fluid.
First breath: - Answers Fluid filling mouth and trachea partially released, air begins
to fill tracheal column.
*Mechanical* - Answers
First active breath sets in motion a chain of events: - Answers - Conversion from fetal
to adult circulation.
- Empties lungs of liquid.
- Establishes neonatal lung volume and characteristics of pulmonary function.
- Decreases pulmonary artery function.
*Describe placental - fetal circulation* - Answers