2026/2027 ACCURATE QUESTIONS WITH
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Description: This comprehensive study guide contains 200 multiple-choice questions
(MCQs) covering all core modules of the Periop 101 curriculum, including aseptic
technique, sterilization, patient positioning, anesthesia, surgical instrumentation,
wound closure, specimen handling, patient safety, and perioperative emergencies.
Each question includes the correct answer marked with ✅ for rapid revision.
Keywords: Periop 101, perioperative nursing, final exam, MCQ, aseptic technique,
sterilization, surgical positioning, anesthesia, instrumentation, patient safety, study
guide, Spring 2026.
Section 1: Aseptic Technique and Infection Control (Q1–
Q30)
1. What is the primary goal of aseptic technique?
A. Reduce surgical costs
B. Prevent microbial contamination of the surgical site ✅
C. Speed up the surgical procedure
D. Improve anesthesia delivery
2. Which of the following is considered a sterile area?
A. The back of a sterile gown
,B. The front of a sterile gown from chest to table level ✅
C. The sleeves below the elbows
D. The collar of the gown
3. How long should a surgical hand scrub last with an antimicrobial agent?
A. 30 seconds
B. 1 minute
C. 3–5 minutes ✅
D. 10 minutes
4. Which item is considered unsterile once touched?
A. The inside of a sterile package
B. The edge of a sterile drape
C. The sterile field border ✅
D. Sterile gloves from a sealed pack
5. What is the minimum distance a non-sterile person must keep from a sterile
field?
A. 6 inches
B. 12 inches ✅
C. 18 inches
D. 24 inches
6. Which microorganism is most commonly associated with surgical site
infections?
A. Escherichia coli
B. Staphylococcus aureus ✅
C. Pseudomonas aeruginosa
D. Candida albicans
7. What is the purpose of a surgical mask?
A. Protect the patient from the nurse's breath
B. Reduce transmission of microorganisms from the surgical team ✅
,C. Filter all airborne particles
D. Provide oxygen to the team
8. When is a surgical mask considered contaminated?
A. After 30 minutes of use
B. When it becomes moist ✅
C. When it is touched by sterile gloves
D. After 2 hours
9. Which of the following is NOT a principle of aseptic technique?
A. Sterile touches sterile
B. Non-sterile touches non-sterile
C. Sterile touching non-sterile remains sterile ✅
D. Items below the waist are considered unsterile
10. What is the correct way to open a sterile package on a table?
A. Open the farthest flap first
B. Open the nearest flap first ✅
C. Tear the package open quickly
D. Drop it onto the field
11. Which of the following is a critical item for sterilization?
A. Blood pressure cuff
B. Surgical instrument ✅
C. Stethoscope
D. Linens
12. What is the Spaulding Classification for items that enter sterile tissue?
A. Critical ✅
B. Semi-critical
C. Non-critical
D. Disposable
, 13. Which of the following is a semi-critical item?
A. Surgical scalpel
B. Endoscope ✅
C. Bedpan
D. Blood pressure cuff
14. What is the minimum temperature for steam sterilization (autoclave) at 15 psi?
A. 100°C
B. 121°C ✅
C. 150°C
D. 180°C
15. How long should items be exposed to steam sterilization at 121°C?
A. 5 minutes
B. 15 minutes ✅
C. 30 minutes
D. 60 minutes
16. Which sterilization method is best for heat-sensitive instruments?
A. Steam autoclave
B. Ethylene oxide (ETO) ✅
C. Dry heat
D. Boiling water
17. What is the purpose of a biological indicator in sterilization?
A. Detect chemical changes
B. Confirm sterility by killing spores ✅
C. Measure temperature
D. Indicate package integrity
18. Which of the following is a chemical indicator used in sterilization?
A. Geobacillus stearothermophilus
B. Autoclave tape ✅