NU 578 - Unit 2 Questions and Answers
Question 1.
Opioids Drugs
Correct Answer: Drugs:
Question 2.
Opioids - MOA
Correct Answer: - Bind to "opiate receptors" in the brain, which disrupts the
transmission of pain signals in the CNS. - Mimic actions of endogenous opiates
(endorphins, enkephalins, dynorphins). - Primarily activate mu receptors, but
also activate Kappa
Question 3.
Opioids - Effect
Correct Answer: * Relieve pain & induce euphoria Also cause sedation,
respiratory depression, miosis, constipation, nausea, & suppress the cough
reflex.
Question 4.
Opioids - Uses
Correct Answer: - Pain relief - Cough suppression - Relief of dyspnea -
Preoperative sedation
Question 5.
Opioids - Side Effects
Correct Answer: Hypotension sedation nausea itching miosis muscle weakness
constipation Urinary Retention Biliary Colic Increased ICP
Question 6.
Treatment of Opioid- Induced Constipation
Correct Answer: methylnaltrexone (Relistor) naloxegol (Movantik) Blocks opioid
receptors in the GI tract * Does not cross blood-brain barrier, so does not
reverse analgesia
Question 7.
Opioids - Drug Interactions
Correct Answer: CNS depressants! Anticholinergics Drugs that lower BP
Question 8.
, Opioids - Contraindications/Warnings
Correct Answer: Decreased respiratory reserve Labor and delivery Inflammatory
Bowel disease Head Injury
Question 9.
Opioids - Patient Educaiton
Correct Answer:
Question 10.
Opioid toxicity
Correct Answer: 3 signs: - coma - pinpoint pupils - respiratory depression - may
be fatal!
Question 11.
Tolerance
Correct Answer: a state in which a drug user needs larger amounts of the drug
to produce the same effect on the body
Question 12.
Physical Dependence
Correct Answer: A state in which an abstinence syndrome will occur if drug use
is abruptly stopped
Question 13.
Abuse
Correct Answer: drug use that is inconsistent with medical or social norms
Question 14.
Addiction
Correct Answer: disease characterized by and individual pathologically pursuing
rewards and relief by substance use and other behaviors
Question 15.
Full opioid agonists
Correct Answer: - Good for severe pain - May give a feeling of euphoria Example:
Morphin, codeine, hydromorphone
Question 16.
Partial opioid agonists (Agonist-antagonist)
Correct Answer: - Good for moderate pain - May act as antagonists at some
receptors and precipitate withdrawal. Example: pentazocine, Suboxone,
Question 1.
Opioids Drugs
Correct Answer: Drugs:
Question 2.
Opioids - MOA
Correct Answer: - Bind to "opiate receptors" in the brain, which disrupts the
transmission of pain signals in the CNS. - Mimic actions of endogenous opiates
(endorphins, enkephalins, dynorphins). - Primarily activate mu receptors, but
also activate Kappa
Question 3.
Opioids - Effect
Correct Answer: * Relieve pain & induce euphoria Also cause sedation,
respiratory depression, miosis, constipation, nausea, & suppress the cough
reflex.
Question 4.
Opioids - Uses
Correct Answer: - Pain relief - Cough suppression - Relief of dyspnea -
Preoperative sedation
Question 5.
Opioids - Side Effects
Correct Answer: Hypotension sedation nausea itching miosis muscle weakness
constipation Urinary Retention Biliary Colic Increased ICP
Question 6.
Treatment of Opioid- Induced Constipation
Correct Answer: methylnaltrexone (Relistor) naloxegol (Movantik) Blocks opioid
receptors in the GI tract * Does not cross blood-brain barrier, so does not
reverse analgesia
Question 7.
Opioids - Drug Interactions
Correct Answer: CNS depressants! Anticholinergics Drugs that lower BP
Question 8.
, Opioids - Contraindications/Warnings
Correct Answer: Decreased respiratory reserve Labor and delivery Inflammatory
Bowel disease Head Injury
Question 9.
Opioids - Patient Educaiton
Correct Answer:
Question 10.
Opioid toxicity
Correct Answer: 3 signs: - coma - pinpoint pupils - respiratory depression - may
be fatal!
Question 11.
Tolerance
Correct Answer: a state in which a drug user needs larger amounts of the drug
to produce the same effect on the body
Question 12.
Physical Dependence
Correct Answer: A state in which an abstinence syndrome will occur if drug use
is abruptly stopped
Question 13.
Abuse
Correct Answer: drug use that is inconsistent with medical or social norms
Question 14.
Addiction
Correct Answer: disease characterized by and individual pathologically pursuing
rewards and relief by substance use and other behaviors
Question 15.
Full opioid agonists
Correct Answer: - Good for severe pain - May give a feeling of euphoria Example:
Morphin, codeine, hydromorphone
Question 16.
Partial opioid agonists (Agonist-antagonist)
Correct Answer: - Good for moderate pain - May act as antagonists at some
receptors and precipitate withdrawal. Example: pentazocine, Suboxone,
