2026/2027 – Complete Exam-Style Questions with Detailed
Rationales | 100% Verified | Pass Guaranteed – A+ Graded
Section A: RSV Pathophysiology & Risk Factors
Q1: A 4-month-old infant presents to the clinic with a 3-day history of rhinorrhea, cough,
and increasing respiratory distress. The parent reports the infant was born prematurely
at 32 weeks gestation. Which pathophysiological mechanism best explains why this
infant is at high risk for severe RSV infection?
A. Excessive production of surfactant leading to alveolar collapse
B. Immature immune system and narrow airways prone to obstruction from
inflammation and mucus
C. Overdeveloped ciliary function causing increased mucus clearance
D. Excessively large alveolar surface area promoting viral replication
Correct Answer: B
Rationale: Premature infants have immature humoral immunity and anatomically narrow
airways; RSV-induced inflammation, edema, and mucus production easily obstruct
these small passages, leading to bronchiolitis and hypoxia. Options A, C, and D describe
physiological states that do not increase RSV severity or are factually incorrect.
Q2: Which statement accurately describes the transmission pattern of respiratory
syncytial virus (RSV)?
A. RSV is transmitted exclusively through airborne droplets over long distances
B. RSV spreads primarily through direct contact with respiratory secretions and
contaminated surfaces
C. RSV requires a vector such as a mosquito for transmission
D. RSV is transmitted only through vertical transmission from mother to fetus
Correct Answer: B
Rationale: RSV spreads via direct contact with infected secretions, droplets, and
fomites, surviving on surfaces for hours. It is not airborne over long distances like
measles, does not require vectors, and is not typically transmitted vertically in utero.
, Q3: A nurse is assessing an infant with suspected RSV bronchiolitis. Which
pathophysiological change is the primary cause of the wheezing and crackles
auscultated on examination?
A. Collapse of the alveolar sacs due to surfactant deficiency
B. Inflammation and obstruction of the small bronchioles by mucus and cellular debris
C. Consolidation of lung parenchyma due to bacterial invasion
D. Spasm of the laryngeal muscles causing upper airway obstruction
Correct Answer: B
Rationale: RSV infects the lower respiratory tract epithelium, causing bronchiolar
inflammation, edema, mucus hypersecretion, and epithelial cell necrosis, which
obstructs small airways and produces wheezing and crackles. Option A describes
respiratory distress syndrome, option C describes bacterial pneumonia, and option D
describes croup.
Q4: Which age group experiences the highest rate of severe RSV disease requiring
hospitalization?
A. Adolescents aged 12-18 years
B. School-age children aged 6-12 years
C. Infants younger than 6 months, particularly those born prematurely
D. Adults over 65 years with no comorbidities
Correct Answer: C
Rationale: Infants under 6 months—especially those born prematurely or with chronic
lung disease, congenital heart disease, or immunodeficiency—have the highest
hospitalization rates due to small airways and immature immunity. While older adults
can be affected, healthy adolescents and school-age children typically experience
milder disease.
Q5: A parent of a 2-month-old asks why their infant cannot simply take cough medicine
to treat RSV. Which explanation by the nurse is most accurate regarding the treatment
approach for RSV?
A. "Antiviral medications are highly effective but must be given intravenously for 7 days."
B. "Treatment is primarily supportive, focusing on oxygenation, hydration, and airway
clearance, as no specific antiviral cure exists for routine cases."
C. "Antibiotics are the treatment of choice to prevent secondary bacterial pneumonia."