MCB 252 Exam 4 (Final) Q & As (Verified
Answers) 2026 Update
severs microtubules by binding chunks and snapping at
junction with unbound monomers. Cuts the tube in the
middle, leaving unstable (+) ends that rapidly collapse -
Correct Answers ✅katanin
regulates spacing of microtubules to form a parallel array
that has less space than MAP arrays - Correct Answers
✅Tau
regulates spacing of microtubules to form a parallel array
with looser spacing - Correct Answers ✅MAP2 and MAP4
binds tubulin dimers and prevents their polymerization
Arrests cells in metaphase by stopping spindle pole extension
- Correct Answers ✅Colchicine, colcemid
Drug that stabilizes microtubules.
Can treat cancer by stopping cell cycle- cell cannot progress
if microtubules are never broken down. - Correct Answers
✅Taxol
turn on and off by phosphorylation and dephosphorylation -
Correct Answers ✅MAP regulation
highly unfavorable, need organizing centers - Correct
Answers ✅Microtubule spontaneous polymerization
,MCB 252 Exam 4 (Final) Q & As (Verified
Answers) 2026 Update
nucleate tubulin dimers as well as cap the - end of a
Microtubule - Correct Answers ✅Microtubule organizing
centers
Centrosome, basal body - Correct Answers ✅Microtubule
organizing center examples
in center of cell
+ ends of microtubules radiate out
duplicates to become both spindle poles in M phase - Correct
Answers ✅centrosome
grab and separate sister chromatids - Correct Answers
✅Spindle poles function
anchors the microtubules in cilium or flagellum - Correct
Answers ✅Basal body
one MT of normal 13 protofilaments and one MT of 10
protofilaments fused together. Makes a figure-8 shape
In cilia and flagella - Correct Answers ✅Microtubule
doublet
,MCB 252 Exam 4 (Final) Q & As (Verified
Answers) 2026 Update
one 13, two 10. Makes a caterpillar shape.
In basal bodies and centrosome
arranged in array of 9 triplets - Correct Answers
✅Microtubule triplet
9 sets of triplets in circle pattern - Correct Answers ✅cilia
and flagella basal bodies
extension of basal bodies. 9 doublets around a central
doublet.
make cilia and flagella protrusion - Correct Answers
✅axoneme
bound to one doublet and move along another doublet. this
slides Microtubules past each other.
Linking proteins prevent the sliding, so Microtubules bend
instead which allows cells to "swim" by wiggling their cilia
and flagella around - Correct Answers ✅motor proteins in
cilia and flagella
body in center of cell, becomes spindle poles in M phase.
, MCB 252 Exam 4 (Final) Q & As (Verified
Answers) 2026 Update
Made of two centrioles - Correct Answers ✅centrosome
details
a minute cylindrical organelle near the nucleus in animal
cells, occurring in pairs and involved in the development of
spindle fibers in cell division. Looks like a basal body -
Correct Answers ✅centrioles
surrounds the centrioles and contains hundreds of ring-
shaped complexes composed of the protein, tubulin
the complexes are the organizing centers for the growth of
the mitotic spindle. - Correct Answers ✅Pericentriolar
material
component of pericentriolar material, localizes around
centrosomes.
Caps the - end of Microtubules and helps nucleation
Part of gamma-tubulin ring complex
allows beta/alpha-tubulin dimers to add (functions similar to
Arp 2/3) - Correct Answers ✅Gamma-Tubulin in yeast
1 in interphase
Answers) 2026 Update
severs microtubules by binding chunks and snapping at
junction with unbound monomers. Cuts the tube in the
middle, leaving unstable (+) ends that rapidly collapse -
Correct Answers ✅katanin
regulates spacing of microtubules to form a parallel array
that has less space than MAP arrays - Correct Answers
✅Tau
regulates spacing of microtubules to form a parallel array
with looser spacing - Correct Answers ✅MAP2 and MAP4
binds tubulin dimers and prevents their polymerization
Arrests cells in metaphase by stopping spindle pole extension
- Correct Answers ✅Colchicine, colcemid
Drug that stabilizes microtubules.
Can treat cancer by stopping cell cycle- cell cannot progress
if microtubules are never broken down. - Correct Answers
✅Taxol
turn on and off by phosphorylation and dephosphorylation -
Correct Answers ✅MAP regulation
highly unfavorable, need organizing centers - Correct
Answers ✅Microtubule spontaneous polymerization
,MCB 252 Exam 4 (Final) Q & As (Verified
Answers) 2026 Update
nucleate tubulin dimers as well as cap the - end of a
Microtubule - Correct Answers ✅Microtubule organizing
centers
Centrosome, basal body - Correct Answers ✅Microtubule
organizing center examples
in center of cell
+ ends of microtubules radiate out
duplicates to become both spindle poles in M phase - Correct
Answers ✅centrosome
grab and separate sister chromatids - Correct Answers
✅Spindle poles function
anchors the microtubules in cilium or flagellum - Correct
Answers ✅Basal body
one MT of normal 13 protofilaments and one MT of 10
protofilaments fused together. Makes a figure-8 shape
In cilia and flagella - Correct Answers ✅Microtubule
doublet
,MCB 252 Exam 4 (Final) Q & As (Verified
Answers) 2026 Update
one 13, two 10. Makes a caterpillar shape.
In basal bodies and centrosome
arranged in array of 9 triplets - Correct Answers
✅Microtubule triplet
9 sets of triplets in circle pattern - Correct Answers ✅cilia
and flagella basal bodies
extension of basal bodies. 9 doublets around a central
doublet.
make cilia and flagella protrusion - Correct Answers
✅axoneme
bound to one doublet and move along another doublet. this
slides Microtubules past each other.
Linking proteins prevent the sliding, so Microtubules bend
instead which allows cells to "swim" by wiggling their cilia
and flagella around - Correct Answers ✅motor proteins in
cilia and flagella
body in center of cell, becomes spindle poles in M phase.
, MCB 252 Exam 4 (Final) Q & As (Verified
Answers) 2026 Update
Made of two centrioles - Correct Answers ✅centrosome
details
a minute cylindrical organelle near the nucleus in animal
cells, occurring in pairs and involved in the development of
spindle fibers in cell division. Looks like a basal body -
Correct Answers ✅centrioles
surrounds the centrioles and contains hundreds of ring-
shaped complexes composed of the protein, tubulin
the complexes are the organizing centers for the growth of
the mitotic spindle. - Correct Answers ✅Pericentriolar
material
component of pericentriolar material, localizes around
centrosomes.
Caps the - end of Microtubules and helps nucleation
Part of gamma-tubulin ring complex
allows beta/alpha-tubulin dimers to add (functions similar to
Arp 2/3) - Correct Answers ✅Gamma-Tubulin in yeast
1 in interphase
