NUR 239 EXAM 5 TB & PNEUMONIA MEDICATIONS
QUESTIONS AND ANSWERS | NUR 239 STUDY GUIDE &
PRACTICE TEST 2026/2027
For all TB and pneumonia meds, what should nurses remember? - ANS ✔✔take 1 hour before and/or 2
hours after meals for oral medications
INH (isoniazid) action: - ANS ✔✔Enters cells and kills actively growing and dormant TB
Prevents synthesis of mycolic acid in TB cell wall
INH use: - ANS ✔✔first-line therapy, prevents and treats ACTIVE TB, most effective drug
INH contraindications: - ANS ✔✔liver disease, children under 2, HIV
What are the primary adverse effects of INH? - ANS ✔✔Hepatotoxicity
Peripheral neuropathy
Hyperglycemia
INH has to be given with ____________ in order to decrease ____________. - ANS ✔✔pyroxidine
(vitamin B6) to decrease neuropathy
What should be monitored for INH? - ANS ✔✔liver function, glucose levels in those with diabetes
What is the use of rifampin? - ANS ✔✔Treatment of active TB, major first line drug, decreases INH
resistance when used together
What is the action of rifampin? - ANS ✔✔Enters cells and kills active TB, inhibits synthesis of RNA
Rifampin is contraindicated in those with: - ANS ✔✔liver disease
What is the most common AE of rifampin? - ANS ✔✔Turns body fluids red orange (urine, tears, sweat,
saliva, etc.) & contacts (recommend these patients to wear glasses)
Rifampin can also cause more severe AE's like: - ANS ✔✔pseudomembranous colitis, hepatotoxicity
You should monitor what with Rifampin? - ANS ✔✔liver function (also look for light colored stools)
Rifampin decreases the effect of: - ANS ✔✔warfarin and oral contraceptives
What is the use of pyrazinamide? - ANS ✔✔First-line drug to treat active TB used with another drug
Contraindications of pyrazinamide? - ANS ✔✔liver disease
Main adverse effects of pyrazinamide? - ANS ✔✔hepatoxicity, GI upset, gout
QUESTIONS AND ANSWERS | NUR 239 STUDY GUIDE &
PRACTICE TEST 2026/2027
For all TB and pneumonia meds, what should nurses remember? - ANS ✔✔take 1 hour before and/or 2
hours after meals for oral medications
INH (isoniazid) action: - ANS ✔✔Enters cells and kills actively growing and dormant TB
Prevents synthesis of mycolic acid in TB cell wall
INH use: - ANS ✔✔first-line therapy, prevents and treats ACTIVE TB, most effective drug
INH contraindications: - ANS ✔✔liver disease, children under 2, HIV
What are the primary adverse effects of INH? - ANS ✔✔Hepatotoxicity
Peripheral neuropathy
Hyperglycemia
INH has to be given with ____________ in order to decrease ____________. - ANS ✔✔pyroxidine
(vitamin B6) to decrease neuropathy
What should be monitored for INH? - ANS ✔✔liver function, glucose levels in those with diabetes
What is the use of rifampin? - ANS ✔✔Treatment of active TB, major first line drug, decreases INH
resistance when used together
What is the action of rifampin? - ANS ✔✔Enters cells and kills active TB, inhibits synthesis of RNA
Rifampin is contraindicated in those with: - ANS ✔✔liver disease
What is the most common AE of rifampin? - ANS ✔✔Turns body fluids red orange (urine, tears, sweat,
saliva, etc.) & contacts (recommend these patients to wear glasses)
Rifampin can also cause more severe AE's like: - ANS ✔✔pseudomembranous colitis, hepatotoxicity
You should monitor what with Rifampin? - ANS ✔✔liver function (also look for light colored stools)
Rifampin decreases the effect of: - ANS ✔✔warfarin and oral contraceptives
What is the use of pyrazinamide? - ANS ✔✔First-line drug to treat active TB used with another drug
Contraindications of pyrazinamide? - ANS ✔✔liver disease
Main adverse effects of pyrazinamide? - ANS ✔✔hepatoxicity, GI upset, gout
