PSYCHIATRIC MENTAL HEALTH NURSE PRACTITIONER EXAM
TEST BANK ACTUAL 2026/2027 PRACTICE QUESTIONS AND STUDY
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Question 1
A 45-year-old patient presents with anhedonia, fatigue, and sleep
disturbances for the last two months. As a PMHNP, which initial
diagnostic step is most appropriate?
A. Order a brain MRI
B. Conduct a comprehensive psychiatric interview
C. Begin antidepressant therapy immediately
D. Recommend mindfulness training
Correct Answer: B
Rationale: A comprehensive psychiatric interview allows for
thorough assessment of history, symptoms, and differential
diagnoses before initiating treatment. Imaging is reserved for
suspected neurological causes, and interventions should follow a
confirmed assessment.
,Question 2
A 24-year-old graduate student presents with a 10-month history of
persistent low mood, anhedonia, profound fatigue, sleeping 12 hours
daily, 15-pound weight gain, and "leaden paralysis." He denies mood
reactivity. What is the most likely specifier for his Major Depressive
Disorder?
A. With atypical features
B. With melancholic features
C. With catatonic features
D. With seasonal pattern
Correct Answer: B
Rationale: Melancholic features require distinct quality of depressed
mood, lack of mood reactivity, and at least three of: morning
worsening, early morning awakening, psychomotor retardation,
significant anorexia/weight loss, excessive guilt, or worse mood in
the morning. While hypersomnia and weight gain are associated
with atypical features, the lack of mood reactivity points to
melancholia.
Question 3
A patient reports episodes of feeling "outside of herself," watching
her life from a distance, for 6 months. These episodes cause
significant distress. She denies trauma history, panic attacks, or
substance use. What is the most likely diagnosis?
,A. Depersonalization/Derealization Disorder
B. Panic Disorder
C. Posttraumatic Stress Disorder
D. Generalized Anxiety Disorder
Correct Answer: A
Rationale: Depersonalization/Derealization Disorder involves
persistent/recurrent experiences of depersonalization or
derealization with intact reality testing, causing clinically significant
distress. The absence of a traumatic stressor rules out PTSD, and
absence of panic attacks rules out Panic Disorder.
Question 4
A 40-year-old male reports anxiety, palpitations, and fear of having
another panic attack. He avoids public spaces and has stopped riding
the subway. Which diagnosis best matches his symptoms?
A. Generalized anxiety disorder
B. Panic disorder with agoraphobia
C. Social anxiety disorder
D. Specific phobia
Correct Answer: B
, Rationale: Panic disorder involves recurrent unexpected attacks with
anxiety about future attacks; avoidance of public places suggests
agoraphobia.
Question 5
A 28-year-old female with a history of PTSD presents with
flashbacks, hypervigilance, and nightmares. She reports using
alcohol to help her sleep. What is the most appropriate first-line
pharmacologic intervention for her nightmares?
A. Quetiapine 25 mg at bedtime
B. Prazosin 1 mg at bedtime
C. Trazodone 50 mg at bedtime
D. Hydroxyzine 25 mg at bedtime
Correct Answer: B
Rationale: Prazosin is an alpha-1 antagonist with robust evidence for
reducing trauma-related nightmares in PTSD. While trazodone and
quetiapine are used for sleep, prazosin is the guideline-supported
first-line agent specifically for PTSD-associated nightmares.
Question 6
During a suicide intervention with your 28-year-old male patient, to
which agreement should you ask for his consent, verbally or in
writing?