NUR 352 FINAL EXAM | COMPREHENSIVE NURSING STUDY GUIDE, PRACTICE
QUESTIONS & ANSWERS 2026/2027
The nurse is preparing to administer morning medications to four clients. Which client has the greatest
risk of medication toxicity?
A. A 74 year old client prescribed four medications for hypertension.
B. A 52 year old client with renal failure on hemodialysis.
C. A 67 year old client receiving three medications that are highly protein bound.
D. A 38 year old client with a serum albumin level of 6.2 g/dL. - ANS ✔✔A 67 year old client receiving
three medications that are highly protein bound.
Which reported statement by the client is of greatest concern when taking a medication to treat
glaucoma?
A.
"After starting brimonidine, I began experiencing dry mouth."
B.
"I noticed the color of my eyes is becoming darker brown after starting the latanoprost."
C.
"I was taking dorzolamide and developed conjunctivitis."
D.
"I am experiencing sensitivity to light while taking timolol." - ANS ✔✔C.
"I was taking dorzolamide and developed conjunctivitis."
A nurse is caring for a client with challenges in memory recall. The client is being treated with a N-
methyl-D-aspartate (NMDA) receptor antagonist medication. Which disease is part of the client's
history?
A.
Seizure disorder
B.
Parkinson disease
C.
Multiple sclerosis
D.
Alzheimer disease - ANS ✔✔D.
Alzheimer disease
The nurse has administered the prescribed dose of an analgesic medication to a client. When
considering the nursing process, what is the nurse's next responsibility to the client?
A.
Evaluating effectiveness of therapy
B.
Updating the plan of care as needed
,C.
Assessing vital signs
D.
Planning non-medication interventions - ANS ✔✔Evaluating effectiveness of therapy
A client has been prescribed diphenhydramine 500 mg for the treatment of a mild allergic reaction. After
reviewing a drug reference manual, hte nurse identifies that the dose is incorrect. What is the priority
action by the nurse at this time?
A.
Assess the client for signs of anaphylaxis.
B.
Hold the medication and notify the prescriber.
C.
Contact the pharmacist to double-check the dose parameters.
D.
Administer the recommended dose as listed in the drug reference manual. - ANS ✔✔Hold the
medication and notify the prescriber.
A client with schizophrenia is starting clozapine therapy. Which information is highest priority to include
in client teaching?
A.
The client should have periodic fasting glucose levels drawn.
B.
The client should monitor for weight gain and adhere to a healthy diet.
C.
The client must have regular white blood cell count (WBC) levels drawn.
D.
The client should report fine hand tremors to the health care provider. - ANS ✔✔The client must have
regular white blood cell count (WBC) levels drawn.
Which laboratory value for a client who has recently been prescribed misoprostol for peptic ulcer disease
would require immediate action by the nurse?
A.
Hemoglobin 10.2 mg/dL
B.
Serum sodium 133 mEq/dL
C.
Arterial pH 7.46
D.
Hma chorionic gonadotropin 30 mlU/mL - ANS ✔✔Hma chorionic gonadotropin 30 mlU/mL
A nurse is preparing to administer interferon beta-1b to the client with multiple sclerosis. Which nursing
intervention is performed prior to the administration of the medicaiton?
A.
,Administer acetaminophen or ibuprofen as prescribed.
B.
Complete a full set of vital signs.
C.
Perform a depression survey.
D.
Assess laboratory values such as complete blood count and liver function tests. - ANS ✔✔Administer
acetaminophen or ibuprofen as prescribed.
A client with major depressive disorder is prescribed phenelzine by a provider. Which client teaching is
the highest priority?
A.
Phenelzine interacts with many foods and medications.
B.
Continue taking phenelzine even after mood improves.
C.
Phenelzine's full therapeutic effect may take 6 to 8 weeks.
D.
Phenelzine may cause insomnia and some sexual side effects - ANS ✔✔Phenelzine interacts with many
foods and medications.
A nurse is reviewing a client's most recent hemoglobin A1c level of 8.7%. What instruction will the nurse
provide to the client based upon this finding?
A.
"The lab value can be altered significantly since you were not fasting. We should repeat the test in 2
weeks."
B.
"This result indicates that your diabetes is not well controlled. Your provider may adjust your medication
regimen."
C.
"This test is not a diagnostic measurement of diabetes, rather it is a guide for medication dosing."
D.
"Your hemoglobin A1c lab value is normal, and no further action needs to be taken." - ANS ✔✔"This
result indicates that your diabetes is not well controlled. Your provider may adjust your medication
regimen."
The nurse is preparing to administer etanercept to a client with rheumatoid arthritis. Which assessment
finding(s) would alert the nurse to potential contraindications to this medication?
A.
Bilateral crackles in the lung bases
B.
2+ pitting edema of the right lower extremity
C.
Platelet count of 135,000 x 103/mcgL
D.
, A tuberculin skin test with induration measuring 10 mm
E.
Hyperactive bowel sounds in all four abdominal quadrants - ANS ✔✔Bilateral crackles in the lung bases
A tuberculin skin test with induration measuring 10 mm
A client with an extensive cardiac history is prescribed omeprazole. The nurse reviews the medication
history and the client is also prescribed clopidogrel, metoprolol, and furosemide. Which instructions
should the nurse provide to the client regarding the medications.
A.
"Furosemide is taken in the morning, and the metoprolol is taken at night."
B.
"Clopidogrel should be taken 12 hours apart from the omeprazole."
C.
"Clopidogrel, metoprolol, and furosemide can be taken together, but the omeprazole needs to be taken
4 hours after the other medications."
D.
"Take all the medications with food in the morning." - ANS ✔✔"Clopidogrel should be taken 12 hours
apart from the omeprazole."
A client who was prescribed nitrofurantoin for a urinary tract infection 1 week ago calls to report the
symptoms have returned. What is the most appropriate response by the nurse?
A.
"You need to restart the antibiotic since your symptoms are back."
B.
"Did you complete the full course of antibiotic as directed?"
C.
"It is common for symptoms to return after completing the antibiotic."
D.
"It is likely that you have another infection. Do you have a fever?" - ANS ✔✔"Did you complete the full
course of antibiotic as directed?"
The client is prescribed morphine to be taken postoperatively. Which condition in the client's past
medical history might be a contraindication to taking this medication?
A.
Renal disease
B.
Emphysema
C.
Hypertension
D.
Gout - ANS ✔✔Emphysema
A client asks why they should not give their 10 month old child ibuprofen after receiving vaccinations.
Which response by the nurse is correct?
QUESTIONS & ANSWERS 2026/2027
The nurse is preparing to administer morning medications to four clients. Which client has the greatest
risk of medication toxicity?
A. A 74 year old client prescribed four medications for hypertension.
B. A 52 year old client with renal failure on hemodialysis.
C. A 67 year old client receiving three medications that are highly protein bound.
D. A 38 year old client with a serum albumin level of 6.2 g/dL. - ANS ✔✔A 67 year old client receiving
three medications that are highly protein bound.
Which reported statement by the client is of greatest concern when taking a medication to treat
glaucoma?
A.
"After starting brimonidine, I began experiencing dry mouth."
B.
"I noticed the color of my eyes is becoming darker brown after starting the latanoprost."
C.
"I was taking dorzolamide and developed conjunctivitis."
D.
"I am experiencing sensitivity to light while taking timolol." - ANS ✔✔C.
"I was taking dorzolamide and developed conjunctivitis."
A nurse is caring for a client with challenges in memory recall. The client is being treated with a N-
methyl-D-aspartate (NMDA) receptor antagonist medication. Which disease is part of the client's
history?
A.
Seizure disorder
B.
Parkinson disease
C.
Multiple sclerosis
D.
Alzheimer disease - ANS ✔✔D.
Alzheimer disease
The nurse has administered the prescribed dose of an analgesic medication to a client. When
considering the nursing process, what is the nurse's next responsibility to the client?
A.
Evaluating effectiveness of therapy
B.
Updating the plan of care as needed
,C.
Assessing vital signs
D.
Planning non-medication interventions - ANS ✔✔Evaluating effectiveness of therapy
A client has been prescribed diphenhydramine 500 mg for the treatment of a mild allergic reaction. After
reviewing a drug reference manual, hte nurse identifies that the dose is incorrect. What is the priority
action by the nurse at this time?
A.
Assess the client for signs of anaphylaxis.
B.
Hold the medication and notify the prescriber.
C.
Contact the pharmacist to double-check the dose parameters.
D.
Administer the recommended dose as listed in the drug reference manual. - ANS ✔✔Hold the
medication and notify the prescriber.
A client with schizophrenia is starting clozapine therapy. Which information is highest priority to include
in client teaching?
A.
The client should have periodic fasting glucose levels drawn.
B.
The client should monitor for weight gain and adhere to a healthy diet.
C.
The client must have regular white blood cell count (WBC) levels drawn.
D.
The client should report fine hand tremors to the health care provider. - ANS ✔✔The client must have
regular white blood cell count (WBC) levels drawn.
Which laboratory value for a client who has recently been prescribed misoprostol for peptic ulcer disease
would require immediate action by the nurse?
A.
Hemoglobin 10.2 mg/dL
B.
Serum sodium 133 mEq/dL
C.
Arterial pH 7.46
D.
Hma chorionic gonadotropin 30 mlU/mL - ANS ✔✔Hma chorionic gonadotropin 30 mlU/mL
A nurse is preparing to administer interferon beta-1b to the client with multiple sclerosis. Which nursing
intervention is performed prior to the administration of the medicaiton?
A.
,Administer acetaminophen or ibuprofen as prescribed.
B.
Complete a full set of vital signs.
C.
Perform a depression survey.
D.
Assess laboratory values such as complete blood count and liver function tests. - ANS ✔✔Administer
acetaminophen or ibuprofen as prescribed.
A client with major depressive disorder is prescribed phenelzine by a provider. Which client teaching is
the highest priority?
A.
Phenelzine interacts with many foods and medications.
B.
Continue taking phenelzine even after mood improves.
C.
Phenelzine's full therapeutic effect may take 6 to 8 weeks.
D.
Phenelzine may cause insomnia and some sexual side effects - ANS ✔✔Phenelzine interacts with many
foods and medications.
A nurse is reviewing a client's most recent hemoglobin A1c level of 8.7%. What instruction will the nurse
provide to the client based upon this finding?
A.
"The lab value can be altered significantly since you were not fasting. We should repeat the test in 2
weeks."
B.
"This result indicates that your diabetes is not well controlled. Your provider may adjust your medication
regimen."
C.
"This test is not a diagnostic measurement of diabetes, rather it is a guide for medication dosing."
D.
"Your hemoglobin A1c lab value is normal, and no further action needs to be taken." - ANS ✔✔"This
result indicates that your diabetes is not well controlled. Your provider may adjust your medication
regimen."
The nurse is preparing to administer etanercept to a client with rheumatoid arthritis. Which assessment
finding(s) would alert the nurse to potential contraindications to this medication?
A.
Bilateral crackles in the lung bases
B.
2+ pitting edema of the right lower extremity
C.
Platelet count of 135,000 x 103/mcgL
D.
, A tuberculin skin test with induration measuring 10 mm
E.
Hyperactive bowel sounds in all four abdominal quadrants - ANS ✔✔Bilateral crackles in the lung bases
A tuberculin skin test with induration measuring 10 mm
A client with an extensive cardiac history is prescribed omeprazole. The nurse reviews the medication
history and the client is also prescribed clopidogrel, metoprolol, and furosemide. Which instructions
should the nurse provide to the client regarding the medications.
A.
"Furosemide is taken in the morning, and the metoprolol is taken at night."
B.
"Clopidogrel should be taken 12 hours apart from the omeprazole."
C.
"Clopidogrel, metoprolol, and furosemide can be taken together, but the omeprazole needs to be taken
4 hours after the other medications."
D.
"Take all the medications with food in the morning." - ANS ✔✔"Clopidogrel should be taken 12 hours
apart from the omeprazole."
A client who was prescribed nitrofurantoin for a urinary tract infection 1 week ago calls to report the
symptoms have returned. What is the most appropriate response by the nurse?
A.
"You need to restart the antibiotic since your symptoms are back."
B.
"Did you complete the full course of antibiotic as directed?"
C.
"It is common for symptoms to return after completing the antibiotic."
D.
"It is likely that you have another infection. Do you have a fever?" - ANS ✔✔"Did you complete the full
course of antibiotic as directed?"
The client is prescribed morphine to be taken postoperatively. Which condition in the client's past
medical history might be a contraindication to taking this medication?
A.
Renal disease
B.
Emphysema
C.
Hypertension
D.
Gout - ANS ✔✔Emphysema
A client asks why they should not give their 10 month old child ibuprofen after receiving vaccinations.
Which response by the nurse is correct?
