NR 293 ACID-CONTROLLING DRUGS CHAPTER 50 | COMPREHENSIVE
PHARMACOLOGY STUDY GUIDE, PRACTICE QUESTIONS & ANSWERS 2026/2027
What are the functions of antacids? - correct answer ✔✔Neutralize acid secretions (decrease acidity,
decrease pain)
*Do not prevent* overproduction of acid.
Promote gastric mucosal defensive mechanisms.
Stimulate secretion of mucus, bicarbonate and prostaglandins.
What are the indications for antacids? - correct answer ✔✔Acute relief of symptoms (ie pain) associated
with acid-related disorders (peptic ulcers, gastritis, gastric hyperacidity and heart burn)
What are the contraindications of antacids? - correct answer ✔✔Allergy
Severe RF
Electrolyte disturbance
GI obstruction
Pregnancy (usually safe, consult HCP first)
What are the adverse effects of antacids? - correct answer ✔✔Product specific
May mask symptoms of serious underlying disease.
What are the interactions with antacids? - correct answer ✔✔Chelation (binds and inactivates other
drug)
Adsorption (decreased absorption of other drug)
*Do not give antacids within 1-2 hours of other medications.*
What are the functions of histamine 2 receptor antagonists? - correct answer ✔✔"tidine"
Antihistamine: Suppresses acid secretion by blocking the H2 receptors on acid-producing parietal cells.
What are the indications for histamine 2 receptor antagonists? - correct answer ✔✔Treatment of GERD,
PUD, erosive esophagitis, adjunct therapy to control upper GI bleeding, Zollinger-Ellison syndrome.
Prophylaxis of stress ulcers
PHARMACOLOGY STUDY GUIDE, PRACTICE QUESTIONS & ANSWERS 2026/2027
What are the functions of antacids? - correct answer ✔✔Neutralize acid secretions (decrease acidity,
decrease pain)
*Do not prevent* overproduction of acid.
Promote gastric mucosal defensive mechanisms.
Stimulate secretion of mucus, bicarbonate and prostaglandins.
What are the indications for antacids? - correct answer ✔✔Acute relief of symptoms (ie pain) associated
with acid-related disorders (peptic ulcers, gastritis, gastric hyperacidity and heart burn)
What are the contraindications of antacids? - correct answer ✔✔Allergy
Severe RF
Electrolyte disturbance
GI obstruction
Pregnancy (usually safe, consult HCP first)
What are the adverse effects of antacids? - correct answer ✔✔Product specific
May mask symptoms of serious underlying disease.
What are the interactions with antacids? - correct answer ✔✔Chelation (binds and inactivates other
drug)
Adsorption (decreased absorption of other drug)
*Do not give antacids within 1-2 hours of other medications.*
What are the functions of histamine 2 receptor antagonists? - correct answer ✔✔"tidine"
Antihistamine: Suppresses acid secretion by blocking the H2 receptors on acid-producing parietal cells.
What are the indications for histamine 2 receptor antagonists? - correct answer ✔✔Treatment of GERD,
PUD, erosive esophagitis, adjunct therapy to control upper GI bleeding, Zollinger-Ellison syndrome.
Prophylaxis of stress ulcers
