8-Menopause Hormone Therapy (MHT) Exam Questions & Answers (Grade A+).docx

8-Menopause Hormone Therapy (MHT)
Exam Questions & Answers (Grade A+)
Menopause -
correct answer ✅Complete/near complete, ovarian follicular
depletion, with resulting hypoestrogenemia and high FSH


hallmark sxs:
-hot flashes


long term implications:
-Bone loss
-CV disease
-Dementia (limited/conflicting data)
-Skin changes (dec collagen--> aging/wrinkles)
-Body composition changes (lean mass-->fat)
-Balance/coordination impairment


menopause tx -
correct answer ✅Menopause Hormone Therapy (MHT)
-Estrogen w/ or w/o progestin

,8-Menopause Hormone Therapy (MHT)
Exam Questions & Answers (Grade A+)
MHT use -
correct answer ✅Short-term (i.e., 6 months to 5 years) tx of
menopause sxs


Osteoporosis with menopause sxs


Not used for:
-Monotherapy osteoporosis tx/prevention
-Prevention of CHD
-Prevention of dementia


MHT risks 50-59yo -
correct answer ✅Counsel women considering HRT on potential
risks/benefits for 5 years of use based on data for women in their
50s
***problems occur in older women***


Overall risks in younger postmenopausal women are considerably
lower than those for older women
-Younger postmenopausal women have lower baseline risk of CHD,
stroke, VTE, and breast cancer

, 8-Menopause Hormone Therapy (MHT)
Exam Questions & Answers (Grade A+)

Endometrial hyperplasia
-Risk of hyperplasia & carcinoma w/in 1 year in 20-50% of women
received unopposed estrogen
-Risk largely abolished by concurrent therapy with a progestin
(either cyclic or continuous dosing)


MHT potential risks -
correct answer ✅Gallbladder disease
Urinary incontinence
Bronchospasm
Uterine leiomyomas
SLE
Epilepsy
Dry eye syndrome


MHT potential benefits -
correct answer ✅Recurrent UTIs (vaginal preps)
Urinary incontinence
Falls