COMLEX-USA Level 2-CE ACTUAL EXAM ALL
QUESTIONS AND ANSWERS ALREADY
GRADED A+. 100% VERIFIED SOLUTIONS |
UPDATED PER LATEST GUIDELINES |
GRADED A+
1. A 60-year-old man presents with painless jaundice, weight loss, and clay-colored stools.
What is the most likely diagnosis?
A) Hepatitis C
B) Primary biliary cholangitis
C) Pancreatic cancer
D) Cholelithiasis
Answer: C) Pancreatic cancer
Rationale: Painless jaundice with weight loss is a classic presentation for pancreatic
adenocarcinoma, often caused by obstruction of the common bile duct.
2. A 28-year-old woman has acute onset of dyspnea, pleuritic chest pain, and tachycardia after
long air travel. Which of the following is the most likely diagnosis?
A) Pneumonia
B) Pulmonary embolism
C) Pneumothorax
D) Myocardial infarction
Answer: B) Pulmonary embolism
Rationale: This patient has several classic risk factors and symptoms for a pulmonary embolism,
including recent immobilization from long travel and acute pleuritic chest pain.
3. A 14-year-old boy with sickle cell disease presents with fever, cough, and chest pain. What
is the most likely causative organism?
, A) Pseudomonas aeruginosa
B) Streptococcus pneumoniae
C) Mycoplasma pneumoniae
D) Haemophilus influenzae
Answer: B) Streptococcus pneumoniae
Rationale: Due to functional asplenia from repeated sickling, patients with sickle cell disease are
at increased risk for encapsulated organisms like Streptococcus pneumoniae.
4. A 50-year-old man with a history of alcohol use disorder presents with confusion,
ophthalmoplegia, and ataxia. Which vitamin deficiency is responsible?
A) Vitamin B1 (Thiamine)
B) Vitamin B12 (Cobalamin)
C) Vitamin B6 (Pyridoxine)
D) Folate
Answer: A) Vitamin B1 (Thiamine)
Rationale: This is a classic presentation of Wernicke's encephalopathy, an emergency caused by
a thiamine deficiency.
5. A 45-year-old man presents with polyuria, polydipsia, hypernatremia, and dilute urine.
Which condition is most likely?
A) SIADH
B) Type 2 diabetes mellitus
C) Diabetes insipidus
D) Psychogenic polydipsia
Answer: C) Diabetes insipidus
Rationale: The inability to concentrate urine leading to hypernatremia and dilute urine is the
hallmark of diabetes insipidus.
6. A 30-year-old woman presents with proptosis, heat intolerance, and weight loss. What is
the most likely diagnosis?
A) Toxic multinodular goiter
B) Graves disease
C) Subacute thyroiditis
D) Hashimoto thyroiditis
Answer: B) Graves disease
Rationale: The combination of hyperthyroidism (heat intolerance, weight loss) and specific eye
findings like proptosis points to Graves' disease.
QUESTIONS AND ANSWERS ALREADY
GRADED A+. 100% VERIFIED SOLUTIONS |
UPDATED PER LATEST GUIDELINES |
GRADED A+
1. A 60-year-old man presents with painless jaundice, weight loss, and clay-colored stools.
What is the most likely diagnosis?
A) Hepatitis C
B) Primary biliary cholangitis
C) Pancreatic cancer
D) Cholelithiasis
Answer: C) Pancreatic cancer
Rationale: Painless jaundice with weight loss is a classic presentation for pancreatic
adenocarcinoma, often caused by obstruction of the common bile duct.
2. A 28-year-old woman has acute onset of dyspnea, pleuritic chest pain, and tachycardia after
long air travel. Which of the following is the most likely diagnosis?
A) Pneumonia
B) Pulmonary embolism
C) Pneumothorax
D) Myocardial infarction
Answer: B) Pulmonary embolism
Rationale: This patient has several classic risk factors and symptoms for a pulmonary embolism,
including recent immobilization from long travel and acute pleuritic chest pain.
3. A 14-year-old boy with sickle cell disease presents with fever, cough, and chest pain. What
is the most likely causative organism?
, A) Pseudomonas aeruginosa
B) Streptococcus pneumoniae
C) Mycoplasma pneumoniae
D) Haemophilus influenzae
Answer: B) Streptococcus pneumoniae
Rationale: Due to functional asplenia from repeated sickling, patients with sickle cell disease are
at increased risk for encapsulated organisms like Streptococcus pneumoniae.
4. A 50-year-old man with a history of alcohol use disorder presents with confusion,
ophthalmoplegia, and ataxia. Which vitamin deficiency is responsible?
A) Vitamin B1 (Thiamine)
B) Vitamin B12 (Cobalamin)
C) Vitamin B6 (Pyridoxine)
D) Folate
Answer: A) Vitamin B1 (Thiamine)
Rationale: This is a classic presentation of Wernicke's encephalopathy, an emergency caused by
a thiamine deficiency.
5. A 45-year-old man presents with polyuria, polydipsia, hypernatremia, and dilute urine.
Which condition is most likely?
A) SIADH
B) Type 2 diabetes mellitus
C) Diabetes insipidus
D) Psychogenic polydipsia
Answer: C) Diabetes insipidus
Rationale: The inability to concentrate urine leading to hypernatremia and dilute urine is the
hallmark of diabetes insipidus.
6. A 30-year-old woman presents with proptosis, heat intolerance, and weight loss. What is
the most likely diagnosis?
A) Toxic multinodular goiter
B) Graves disease
C) Subacute thyroiditis
D) Hashimoto thyroiditis
Answer: B) Graves disease
Rationale: The combination of hyperthyroidism (heat intolerance, weight loss) and specific eye
findings like proptosis points to Graves' disease.
